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OR1I1 olfactory receptor family 1 subfamily I member 1 [ Homo sapiens (human) ]

Gene ID: 126370, updated on 11-Jun-2021

Summary

Official Symbol
OR1I1provided by HGNC
Official Full Name
olfactory receptor family 1 subfamily I member 1provided by HGNC
Primary source
HGNC:HGNC:8207
See related
Ensembl:ENSG00000094661
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR1I1P; OR1I1Q; OR19-20
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR1I1 in Genome Data Viewer
Location:
19p13.12
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (15082211..15092970)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (15193022..15203781)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 13248 Neighboring gene coiled-coil domain containing 105 Neighboring gene caspase 14 Neighboring gene synapse defective Rho GTPase homolog 1 Neighboring gene ilvB acetolactate synthase like Neighboring gene olfactory receptor family 10 subfamily B member 1 pseudogene

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 1I1
Names
olfactory receptor 19-20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004713.2NP_001004713.1  olfactory receptor 1I1

    See identical proteins and their annotated locations for NP_001004713.1

    Status: VALIDATED

    Source sequence(s)
    AC004699, AC004794
    Consensus CDS
    CCDS32937.1
    UniProtKB/Swiss-Prot
    O60431
    Related
    ENSP00000493393.1, ENST00000641398.1
    Conserved Domains (2) summary
    pfam00001
    Location:41290
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:31305
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    15082211..15092970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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