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TNFAIP8L1 TNF alpha induced protein 8 like 1 [ Homo sapiens (human) ]

Gene ID: 126282, updated on 1-Jun-2020

Summary

Official Symbol
TNFAIP8L1provided by HGNC
Official Full Name
TNF alpha induced protein 8 like 1provided by HGNC
Primary source
HGNC:HGNC:28279
See related
Ensembl:ENSG00000185361 MIM:615869
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TIPE1
Expression
Ubiquitous expression in liver (RPKM 6.4), spleen (RPKM 5.8) and 24 other tissues See more
Orthologs

Genomic context

See TNFAIP8L1 in Genome Data Viewer
Location:
19p13.3
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (4639505..4655568)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (4639527..4655580)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene semaphorin 6B Neighboring gene uncharacterized LOC105372249 Neighboring gene ribosomal protein S10 pseudogene Neighboring gene myeloid derived growth factor Neighboring gene DPP9 antisense RNA 1 Neighboring gene dipeptidyl peptidase 9

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ39932, MGC17791

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
negative regulation of TOR signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of TOR signaling ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
tumor necrosis factor alpha-induced protein 8-like protein 1
Names
TNF alpha-induced protein 8-like protein 1
TNFAIP8-like protein 1
oxidative stress-regulated gene-beta
oxy-beta
tumor necrosis factor, alpha induced protein 8 like 1
tumor necrosis factor, alpha-induced protein 8-like protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001167942.1NP_001161414.1  tumor necrosis factor alpha-induced protein 8-like protein 1

    See identical proteins and their annotated locations for NP_001161414.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC005339, AC011498
    Consensus CDS
    CCDS12132.1
    UniProtKB/Swiss-Prot
    Q8WVP5
    Related
    ENSP00000444215.1, ENST00000536716.1
    Conserved Domains (1) summary
    pfam05527
    Location:5183
    DUF758; Domain of unknown function (DUF758)
  2. NM_152362.3NP_689575.2  tumor necrosis factor alpha-induced protein 8-like protein 1

    See identical proteins and their annotated locations for NP_689575.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC005339, BX282702
    Consensus CDS
    CCDS12132.1
    UniProtKB/Swiss-Prot
    Q8WVP5
    Related
    ENSP00000331827.3, ENST00000327473.9
    Conserved Domains (1) summary
    pfam05527
    Location:5183
    DUF758; Domain of unknown function (DUF758)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    4639505..4655568
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527680.2XP_011525982.1  tumor necrosis factor alpha-induced protein 8-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011525982.1

    UniProtKB/Swiss-Prot
    Q8WVP5
    Conserved Domains (1) summary
    pfam05527
    Location:5183
    DUF758; Domain of unknown function (DUF758)
  2. XM_005259487.3XP_005259544.1  tumor necrosis factor alpha-induced protein 8-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005259544.1

    UniProtKB/Swiss-Prot
    Q8WVP5
    Conserved Domains (1) summary
    pfam05527
    Location:5183
    DUF758; Domain of unknown function (DUF758)
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