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Cetn3 centrin 3 [ Mus musculus (house mouse) ]

Gene ID: 12626, updated on 9-Sep-2018

Summary

Official Symbol
Cetn3provided by MGI
Official Full Name
centrin 3provided by MGI
Primary source
MGI:MGI:1097706
See related
Ensembl:ENSMUSG00000021537
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MmCEN3
Expression
Biased expression in CNS E18 (RPKM 18.1), CNS E11.5 (RPKM 17.0) and 14 other tissues See more
Orthologs

Genomic context

See Cetn3 in Genome Data Viewer
Location:
13; 13 C3
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (81783249..81797157)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (81922291..81936156)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene polymerase (RNA) III (DNA directed) polypeptide G Neighboring gene metallo-beta-lactamase domain containing 2 Neighboring gene predicted gene, 32836 Neighboring gene predicted gene, 41008

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein beta/gamma-subunit complex binding IDA
Inferred from Direct Assay
more info
PubMed 
calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
calcium-mediated signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
microtubule nucleation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic spindle pole body duplication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spindle pole body duplication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
centriole IDA
Inferred from Direct Assay
more info
PubMed 
centriole ISO
Inferred from Sequence Orthology
more info
 
centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
centrosome ISO
Inferred from Sequence Orthology
more info
 
ciliary basal body IDA
Inferred from Direct Assay
more info
PubMed 
ciliary transition zone IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
half bridge of spindle pole body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with nucleotide-excision repair factor 2 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
photoreceptor connecting cilium IDA
Inferred from Direct Assay
more info
PubMed 
transcription export complex 2 IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007684.4NP_031710.1  centrin-3

    See identical proteins and their annotated locations for NP_031710.1

    Status: VALIDATED

    Source sequence(s)
    AI851499, AK006891, BY103593
    Consensus CDS
    CCDS26663.1
    UniProtKB/Swiss-Prot
    O35648
    UniProtKB/TrEMBL
    Q545L8
    Related
    ENSMUSP00000022009.8, ENSMUST00000022009.9
    Conserved Domains (1) summary
    cl25352
    Location:15166
    EFh_PEF; The penta-EF hand (PEF) family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

    Range
    81783249..81797157
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006517074.3XP_006517137.1  centrin-3 isoform X1

    Conserved Domains (2) summary
    cd00051
    Location:102157
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam13499
    Location:3090
    EF-hand_7; EF-hand domain pair
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