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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_051553.1 RefSeqGene
- Range
-
5001..45798
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001317000.1 → NP_001303929.1 NACHT, LRR and PYD domains-containing protein 8 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
- Source sequence(s)
-
AY154463, BK001109
- Consensus CDS
-
CCDS82402.1
- UniProtKB/Swiss-Prot
-
Q86W28
- Related
- ENSP00000468121.1, ENST00000590542.1
- Conserved Domains (6) summary
-
- COG4886
Location:810 → 974
- LRR; Leucine-rich repeat (LRR) protein [Transcription]
- cd00116
Location:775 → 988
- LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
- cd08320
Location:41 → 123
- Pyrin_NALPs; Pyrin death domain found in NALP proteins
- sd00033
Location:818 → 846
- LRR_RI; leucine-rich repeat [structural motif]
- sd00034
Location:734 → 760
- LRR_AMN1; leucine-rich repeat [structural motif]
- cl21455
Location:205 → 372
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
NM_001433706.1 → NP_001420635.1 NACHT, LRR and PYD domains-containing protein 8 isoform 3
Status: REVIEWED
- Source sequence(s)
-
AC011470
-
NM_176811.2 → NP_789781.2 NACHT, LRR and PYD domains-containing protein 8 isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
- Source sequence(s)
-
BK001109
- Consensus CDS
-
CCDS12937.1
- UniProtKB/Swiss-Prot
- Q7RTR4, Q86W28
- Related
- ENSP00000291971.3, ENST00000291971.7
- Conserved Domains (5) summary
-
- COG4886
Location:810 → 993
- LRR; Leucine-rich repeat (LRR) protein [Transcription]
- cd00116
Location:781 → 1007
- LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
- cd08320
Location:41 → 123
- Pyrin_NALPs; Pyrin death domain found in NALP proteins
- sd00034
Location:790 → 817
- LRR_AMN1; leucine-rich repeat [structural motif]
- cl21455
Location:205 → 372
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000019.10 Reference GRCh38.p14 Primary Assembly
- Range
-
55947832..55988629
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060943.1 Alternate T2T-CHM13v2.0
- Range
-
59047150..59087952
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054319788.1 → XP_054175763.1 NACHT, LRR and PYD domains-containing protein 8 isoform X1
-
XM_054319789.1 → XP_054175764.1 NACHT, LRR and PYD domains-containing protein 8 isoform X2