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ZNF441 zinc finger protein 441 [ Homo sapiens (human) ]

Gene ID: 126068, updated on 29-Mar-2020

Summary

Official Symbol
ZNF441provided by HGNC
Official Full Name
zinc finger protein 441provided by HGNC
Primary source
HGNC:HGNC:20875
See related
Ensembl:ENSG00000197044
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in thyroid (RPKM 4.2), kidney (RPKM 3.1) and 25 other tissues See more
Orthologs

Genomic context

See ZNF441 in Genome Data Viewer
Location:
19p13.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (11767000..11784078)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (11877815..11894893)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr19.1989 Neighboring gene zinc finger protein 823 Neighboring gene zinc finger protein 491 Neighboring gene zinc finger protein 440

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • FLJ38637

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA polymerase II regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152355.3NP_689568.2  zinc finger protein 441

    See identical proteins and their annotated locations for NP_689568.2

    Status: VALIDATED

    Source sequence(s)
    AC008543, BX649086, DB250168
    Consensus CDS
    CCDS12266.2
    UniProtKB/Swiss-Prot
    Q8N8Z8
    Related
    ENSP00000350576.4, ENST00000357901.5
    Conserved Domains (5) summary
    smart00349
    Location:444
    KRAB; krueppel associated box
    COG5048
    Location:222634
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:589609
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:440
    KRAB; KRAB box
    pfam13465
    Location:601626
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    11767000..11784078
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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