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TRAPPC5 trafficking protein particle complex subunit 5 [ Homo sapiens (human) ]

Gene ID: 126003, updated on 10-Dec-2024

Summary

Official Symbol
TRAPPC5provided by HGNC
Official Full Name
trafficking protein particle complex subunit 5provided by HGNC
Primary source
HGNC:HGNC:23067
See related
Ensembl:ENSG00000181029 AllianceGenome:HGNC:23067
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TRS31
Summary
Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Part of TRAPP complex. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in testis (RPKM 17.0), kidney (RPKM 16.1) and 25 other tissues See more
Orthologs
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Genomic context

See TRAPPC5 in Genome Data Viewer
Location:
19p13.2
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (7680833..7687703)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (7681718..7688588)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (7745719..7752589)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene resistin Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13892 Neighboring gene mast cell expressed membrane protein 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9990 Neighboring gene Sharpr-MPRA regulatory region 435 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:7749795-7749977 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13893 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13894 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13895 Neighboring gene Fc epsilon receptor II Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13896 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13897 Neighboring gene uncharacterized LOC105372262 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13898

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: MCEMP1

Clone Names

  • MGC52424

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in COPII vesicle coating NAS
Non-traceable Author Statement
more info
PubMed 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport NAS
Non-traceable Author Statement
more info
PubMed 
involved_in vesicle coating NAS
Non-traceable Author Statement
more info
PubMed 
involved_in vesicle tethering NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
part_of TRAPP complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of TRAPPI protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of TRAPPII protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of TRAPPII protein complex NAS
Non-traceable Author Statement
more info
PubMed 
part_of TRAPPIII protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of TRAPPIII protein complex NAS
Non-traceable Author Statement
more info
PubMed 
located_in cytoplasm NAS
Non-traceable Author Statement
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
trafficking protein particle complex subunit 5
Names
trafficking protein particle complex 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_055288.2 RefSeqGene

    Range
    5002..11872
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001042461.3NP_001035926.1  trafficking protein particle complex subunit 5

    See identical proteins and their annotated locations for NP_001035926.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-3 encode the same protein.
    Source sequence(s)
    AC008763, BC022836, BG528980, BU736689
    Consensus CDS
    CCDS42490.1
    UniProtKB/Swiss-Prot
    A8K7I6, Q8IUR0
    Related
    ENSP00000399025.1, ENST00000426877.2
    Conserved Domains (1) summary
    cd14943
    Location:24175
    TRAPPC5_Trs31; Trs31 subunit of the TRAPP complex
  2. NM_001042462.2NP_001035927.1  trafficking protein particle complex subunit 5

    See identical proteins and their annotated locations for NP_001035927.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-3 encode the same protein.
    Source sequence(s)
    AC008763, BM841051, BU736689
    Consensus CDS
    CCDS42490.1
    UniProtKB/Swiss-Prot
    A8K7I6, Q8IUR0
    Related
    ENSP00000470262.1, ENST00000596148.3
    Conserved Domains (1) summary
    cd14943
    Location:24175
    TRAPPC5_Trs31; Trs31 subunit of the TRAPP complex
  3. NM_174894.3NP_777554.1  trafficking protein particle complex subunit 5

    See identical proteins and their annotated locations for NP_777554.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1-3 encode the same protein.
    Source sequence(s)
    AC008763, BC042161, BG528980, BI196928, BU736689
    Consensus CDS
    CCDS42490.1
    UniProtKB/Swiss-Prot
    A8K7I6, Q8IUR0
    Related
    ENSP00000316990.4, ENST00000317378.5
    Conserved Domains (1) summary
    cd14943
    Location:24175
    TRAPPC5_Trs31; Trs31 subunit of the TRAPP complex

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    7680833..7687703
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    7681718..7688588
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)