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MBD3L2 methyl-CpG binding domain protein 3 like 2 [ Homo sapiens (human) ]

Gene ID: 125997, updated on 23-Nov-2021

Summary

Official Symbol
MBD3L2provided by HGNC
Official Full Name
methyl-CpG binding domain protein 3 like 2provided by HGNC
Primary source
HGNC:HGNC:18532
See related
Ensembl:ENSG00000230522 MIM:607964
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. The protein has been found in germ cell tumors and some somatic tissues. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
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Genomic context

See MBD3L2 in Genome Data Viewer
Location:
19p13.2
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (7049321..7051735)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (7049332..7051746)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene methyl-CpG binding domain protein 3 like 5 Neighboring gene methyl-CpG binding domain protein 3 like 4 Neighboring gene methyl-CpG binding domain protein 3 like 3 Neighboring gene zinc finger protein 557

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
methyl-CpG-binding domain protein 3-like 2
Names
CTB-25J19.1
MBD3-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144614.4NP_653215.2  methyl-CpG-binding domain protein 3-like 2

    See identical proteins and their annotated locations for NP_653215.2

    Status: REVIEWED

    Source sequence(s)
    AC010606, AF503919
    Consensus CDS
    CCDS42483.1
    UniProtKB/Swiss-Prot
    Q8NHZ7
    Related
    ENSP00000370800.2, ENST00000381393.3
    Conserved Domains (2) summary
    pfam14048
    Location:103193
    MBD_C; C-terminal domain of methyl-CpG binding protein 2 and 3
    pfam16564
    Location:4897
    MBDa; p55-binding region of Methyl-CpG-binding domain proteins MBD

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    7049321..7051735
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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