Format

Send to:

Choose Destination

MICOS13 mitochondrial contact site and cristae organizing system subunit 13 [ Homo sapiens (human) ]

Gene ID: 125988, updated on 1-Jun-2020

Summary

Official Symbol
MICOS13provided by HGNC
Official Full Name
mitochondrial contact site and cristae organizing system subunit 13provided by HGNC
Primary source
HGNC:HGNC:33702
See related
Ensembl:ENSG00000174917 MIM:616658
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
P117; QIL1; MIC13; C19orf70
Expression
Ubiquitous expression in heart (RPKM 20.0), testis (RPKM 19.7) and 25 other tissues See more
Orthologs

Genomic context

See MICOS13 in Genome Data Viewer
Location:
19p13.3
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (5678414..5680896, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (5678425..5680911, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene scaffold attachment factor B Neighboring gene uncharacterized LOC107985320 Neighboring gene hydroxysteroid 11-beta dehydrogenase 1 like Neighboring gene ribosomal protein L36 Neighboring gene lon peptidase 1, mitochondrial

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cristae formation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cristae formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
inner mitochondrial membrane organization IC
Inferred by Curator
more info
PubMed 
Component Evidence Code Pubs
MICOS complex HDA PubMed 
MICOS complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
MICOS complex IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial crista junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial crista junction IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial sorting and assembly machinery complex HDA PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
MICOS complex subunit MIC13
Names
protein QIL1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001308240.1NP_001295169.1  MICOS complex subunit MIC13 isoform 1

    See identical proteins and their annotated locations for NP_001295169.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AA292888, AC011499, AI004554, AI300708, AJ707830, BI827162, CR748109
    Consensus CDS
    CCDS77221.1
    UniProtKB/Swiss-Prot
    Q5XKP0
    UniProtKB/TrEMBL
    A0A140TA86
    Conserved Domains (1) summary
    pfam15884
    Location:32129
    QIL1; Protein QIL1
  2. NM_001365761.1NP_001352690.1  MICOS complex subunit MIC13 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC011499
    Related
    ENSP00000468723.1, ENST00000587950.5
    Conserved Domains (1) summary
    pfam15884
    Location:32129
    QIL1; Protein QIL1
  3. NM_205767.3NP_991330.1  MICOS complex subunit MIC13 isoform 2 precursor

    See identical proteins and their annotated locations for NP_991330.1

    Status: VALIDATED

    Source sequence(s)
    BC009557
    Consensus CDS
    CCDS12143.1
    UniProtKB/Swiss-Prot
    Q5XKP0
    Related
    ENSP00000309561.3, ENST00000309324.8
    Conserved Domains (1) summary
    pfam15884
    Location:9107
    QIL1; Protein QIL1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    5678414..5680896 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527675.2XP_011525977.1  MICOS complex subunit MIC13 isoform X2

    See identical proteins and their annotated locations for XP_011525977.1

    UniProtKB/TrEMBL
    A0A140TA84
    Related
    ENSP00000465739.1, ENST00000590389.5
    Conserved Domains (1) summary
    pfam15884
    Location:32110
    QIL1; Protein QIL1
Support Center