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RAVER1 ribonucleoprotein, PTB binding 1 [ Homo sapiens (human) ]

Gene ID: 125950, updated on 8-Jul-2019

Summary

Official Symbol
RAVER1provided by HGNC
Official Full Name
ribonucleoprotein, PTB binding 1provided by HGNC
Primary source
HGNC:HGNC:30296
See related
Ensembl:ENSG00000161847 MIM:609950
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in spleen (RPKM 11.2), bone marrow (RPKM 11.0) and 25 other tissues See more
Orthologs

Genomic context

See RAVER1 in Genome Data Viewer
Location:
19p13.2
Exon count:
14
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (10316212..10333529, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (10426888..10444314, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger GATA like protein 1 Neighboring gene ferredoxin 2 Neighboring gene intercellular adhesion molecule 3 Neighboring gene tyrosine kinase 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp120 env Tandem affinity purification and mass spectrometry analysis identify ribonucleoprotein PTB-binding 1 protein (RAVER1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells PubMed
Gag-Pol gag-pol Tandem affinity purification and mass spectrometry analysis identify ribonucleoprotein PTB-binding 1 protein (RAVER1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells PubMed
Nef nef Tandem affinity purification and mass spectrometry analysis identify ribonucleoprotein PTB-binding 1 protein (RAVER1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells PubMed
Pr55(Gag) gag Tandem affinity purification and mass spectrometry analysis identify ribonucleoprotein PTB-binding 1 protein (RAVER1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1978

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
ribonucleoprotein PTB-binding 1
Names
protein raver-1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001366174.1NP_001353103.1  ribonucleoprotein PTB-binding 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC011511, AC114271
    Conserved Domains (4) summary
    cd12663
    Location:59129
    RRM1_RAVER1; RNA recognition motif 1 in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)
    cd12665
    Location:133209
    RRM2_RAVER1; RNA recognition motif 2 found in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)
    cd12667
    Location:219306
    RRM3_RAVER1; RNA recognition motif 3 in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)
    cl26464
    Location:364612
    Atrophin-1; Atrophin-1 family
  2. NM_133452.3NP_597709.3  ribonucleoprotein PTB-binding 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    BC037565, BX401103, CR746909, DB446023
    Consensus CDS
    CCDS45960.1
    Related
    ENSP00000482277.1, ENST00000617231.5
    Conserved Domains (4) summary
    cd12663
    Location:59129
    RRM1_RAVER1; RNA recognition motif 1 in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)
    cd12665
    Location:133209
    RRM2_RAVER1; RNA recognition motif 2 found in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)
    cd12667
    Location:219306
    RRM3_RAVER1; RNA recognition motif 3 in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)
    cl26464
    Location:364635
    Atrophin-1; Atrophin-1 family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    10316212..10333529 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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