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RAVER1 ribonucleoprotein, PTB binding 1 [ Homo sapiens (human) ]

Gene ID: 125950, updated on 8-Apr-2018
Official Symbol
RAVER1provided by HGNC
Official Full Name
ribonucleoprotein, PTB binding 1provided by HGNC
Primary source
HGNC:HGNC:30296
See related
Ensembl:ENSG00000161847 MIM:609950; Vega:OTTHUMG00000180409
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in spleen (RPKM 11.2), bone marrow (RPKM 11.0) and 25 other tissues See more
Orthologs
Location:
19p13.2
Exon count:
13
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 19 NC_000019.10 (10316212..10333638, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (10426888..10444314, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger, GATA-like protein 1 Neighboring gene ferredoxin 2 Neighboring gene intercellular adhesion molecule 3 Neighboring gene tyrosine kinase 2

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp120 env Tandem affinity purification and mass spectrometry analysis identify ribonucleoprotein PTB-binding 1 protein (RAVER1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells PubMed
Gag-Pol gag-pol Tandem affinity purification and mass spectrometry analysis identify ribonucleoprotein PTB-binding 1 protein (RAVER1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells PubMed
Nef nef Tandem affinity purification and mass spectrometry analysis identify ribonucleoprotein PTB-binding 1 protein (RAVER1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells PubMed
Pr55(Gag) gag Tandem affinity purification and mass spectrometry analysis identify ribonucleoprotein PTB-binding 1 protein (RAVER1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells PubMed

Go to the HIV-1, Human Interaction Database

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • KIAA1978

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
nucleic acid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
ribonucleoprotein PTB-binding 1
Names
protein raver-1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133452.2NP_597709.2  ribonucleoprotein PTB-binding 1

    See identical proteins and their annotated locations for NP_597709.2

    Status: VALIDATED

    Source sequence(s)
    BC037565, BX401103, CR746909, DB446023
    Consensus CDS
    CCDS45960.1
    UniProtKB/Swiss-Prot
    Q8IY67
    UniProtKB/TrEMBL
    E9PAU2
    Related
    ENSP00000293677.5, OTTHUMP00000264237, ENST00000293677.10, OTTHUMT00000451227
    Conserved Domains (4) summary
    COG0724
    Location:276354
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12663
    Location:76146
    RRM1_RAVER1; RNA recognition motif 1 in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)
    cd12665
    Location:150226
    RRM2_RAVER1; RNA recognition motif 2 found in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)
    cd12667
    Location:236323
    RRM3_RAVER1; RNA recognition motif 3 in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p12 Primary Assembly

    Range
    10316212..10333638 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527671.1XP_011525973.1  ribonucleoprotein PTB-binding 1 isoform X1

    See identical proteins and their annotated locations for XP_011525973.1

    Conserved Domains (4) summary
    COG0724
    Location:276354
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12663
    Location:76146
    RRM1_RAVER1; RNA recognition motif 1 in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)
    cd12665
    Location:150226
    RRM2_RAVER1; RNA recognition motif 2 found in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)
    cd12667
    Location:236323
    RRM3_RAVER1; RNA recognition motif 3 in vertebrate ribonucleoprotein PTB-binding 1 (raver-1)
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