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41 AAA family ATPase [ Escherichia phage T4 ]

Gene ID: 1258700, updated on 16-Jun-2026
Gene symbol
41
Gene description
AAA family ATPase
Locus tag
T4p039
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia phage T4 (nat-host: Escherichia coli)
Lineage
Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Straboviridae; Tevenvirinae; Tequatrovirus
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Sequence:
NC_000866.4 (20612..22039, complement)

NC_000866.4Genomic Context describing neighboring genes Neighboring gene gp61.4 hypothetical protein Neighboring gene Dmd discriminator of mRNA degradation Neighboring gene head vertex assembly chaperone Neighboring gene recombinase Neighboring gene homing endonuclease

Genomic Sequence:
NC_000866.4

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Single-molecule FRET and linear dichroism studies of DNA breathing and helicase binding at replication fork junctions. Phelps C, et al. Proc Natl Acad Sci U S A, 2013 Oct 22. PMID 24062430, Free PMC Article
  2. Mechanistic studies of the T4 DNA (gp41) replication helicase: functional interactions of the C-terminal Tails of the helicase subunits with the T4 (gp59) helicase loader protein. Delagoutte E, et al. J Mol Biol, 2005 Mar 25. PMID 15740739
  3. Control of helicase loading in the coupled DNA replication and recombination systems of bacteriophage T4. Branagan AM, et al. J Biol Chem, 2014 Jan 31. PMID 24338568, Free PMC Article
  4. Bacteriophage T4 genome. Miller ES, et al. Microbiol Mol Biol Rev, 2003 Mar. PMID 12626685, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Gp59-DNA interactions are needed to load Gp41 onto nascent or collapsed replication forks lacking clusters of Gp32 and to coordinate bidirectional replication from T4 origins.
    Title: Control of helicase loading in the coupled DNA replication and recombination systems of bacteriophage T4.
  2. Data indicate that hexameric gp41 helicase binds weakly to the ss-dsDNA junction of a replication fork.
    Title: Single-molecule FRET and linear dichroism studies of DNA breathing and helicase binding at replication fork junctions.
  3. Results examine the interactions of wild type and mutant forms of the gp41 helicase with the T4 gp59 helicase loader and gp32 single-stranded DNA binding proteins.
    Title: Mechanistic studies of the T4 DNA (gp41) replication helicase: functional interactions of the C-terminal Tails of the helicase subunits with the T4 (gp59) helicase loader protein.
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Homology

Preferred Names
AAA family ATPase
NP_049654.1
  • gp41; replicative DNA helicase; ATPase; functional hexamer; forms helicase-primase complex with gp61; required for lagging strand DNA synthesis and processive leading strand DNA synthesis

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000866.4 Reference assembly

    Range
    20612..22039 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_049654.1 AAA family ATPase [Escherichia phage T4]

    See identical proteins and their annotated locations for NP_049654.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P04530
    Conserved Domains (1) summary
    PHA02542
    Location:1 → 475
    41; 41 helicase; Provisional
Nucleotide Protein
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