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Cd82 CD82 antigen [ Mus musculus (house mouse) ]

Gene ID: 12521, updated on 12-May-2024

Summary

Official Symbol
Cd82provided by MGI
Official Full Name
CD82 antigenprovided by MGI
Primary source
MGI:MGI:104651
See related
Ensembl:ENSMUSG00000027215 AllianceGenome:MGI:104651
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C33; IA4; Kai1; Tspan27
Summary
Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including choroid plexus; foregut; limb segment; meninges; and olfactory epithelium. Orthologous to human CD82 (CD82 molecule). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in large intestine adult (RPKM 142.7), duodenum adult (RPKM 91.2) and 22 other tissues See more
Orthologs
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Genomic context

See Cd82 in Genome Data Viewer
Location:
2 E1; 2 51.62 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (93249447..93293295, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (93419102..93462950, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 32745 Neighboring gene predicted gene 13807 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:93264860-93264969 Neighboring gene STARR-positive B cell enhancer ABC_E5946 Neighboring gene microRNA 7001 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:93299170-93299353 Neighboring gene STARR-positive B cell enhancer ABC_E2630 Neighboring gene STARR-positive B cell enhancer ABC_E4482 Neighboring gene predicted gene 10804 Neighboring gene predicted gene, 54115 Neighboring gene predicted gene, 33010

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
CD82 antigen
Names
C33 antigen
inducible membrane protein R2
kangai 1 (suppression of tumorigenicity 6, prostate)
metastasis suppressor Kangai-1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001136055.2NP_001129527.1  CD82 antigen

    See identical proteins and their annotated locations for NP_001129527.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 1. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
    Source sequence(s)
    AK135381, AL732483, BM215013
    Consensus CDS
    CCDS16454.1
    UniProtKB/Swiss-Prot
    P40237
    UniProtKB/TrEMBL
    Q3UII2
    Related
    ENSMUSP00000112158.3, ENSMUST00000116457.9
    Conserved Domains (1) summary
    cd03160
    Location:106228
    CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
  2. NM_001271430.1NP_001258359.1  CD82 antigen

    See identical proteins and their annotated locations for NP_001258359.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
    Source sequence(s)
    AK135381, AK160907, AL732483, BM215013
    Consensus CDS
    CCDS16454.1
    UniProtKB/Swiss-Prot
    P40237
    UniProtKB/TrEMBL
    Q3UII2
    Related
    ENSMUSP00000097287.2, ENSMUST00000099696.8
    Conserved Domains (1) summary
    cd03160
    Location:106228
    CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
  3. NM_001271431.1NP_001258360.1  CD82 antigen

    See identical proteins and their annotated locations for NP_001258360.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 1. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
    Source sequence(s)
    AL732483
    Consensus CDS
    CCDS16454.1
    UniProtKB/Swiss-Prot
    P40237
    UniProtKB/TrEMBL
    Q3UII2
    Conserved Domains (1) summary
    cd03160
    Location:106228
    CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
  4. NM_001271432.1NP_001258361.1  CD82 antigen

    See identical proteins and their annotated locations for NP_001258361.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
    Source sequence(s)
    AL732483
    Consensus CDS
    CCDS16454.1
    UniProtKB/Swiss-Prot
    P40237
    UniProtKB/TrEMBL
    Q3UII2
    Conserved Domains (1) summary
    cd03160
    Location:106228
    CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
  5. NM_001271461.1NP_001258390.1  CD82 antigen

    See identical proteins and their annotated locations for NP_001258390.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 1. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
    Source sequence(s)
    AL732483
    Consensus CDS
    CCDS16454.1
    UniProtKB/Swiss-Prot
    P40237
    UniProtKB/TrEMBL
    Q3UII2
    Conserved Domains (1) summary
    cd03160
    Location:106228
    CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
  6. NM_001271462.1NP_001258391.1  CD82 antigen

    See identical proteins and their annotated locations for NP_001258391.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 1. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
    Source sequence(s)
    AL732483
    Consensus CDS
    CCDS16454.1
    UniProtKB/Swiss-Prot
    P40237
    UniProtKB/TrEMBL
    Q3UII2
    Related
    ENSMUSP00000106888.2, ENSMUST00000111257.8
    Conserved Domains (1) summary
    cd03160
    Location:106228
    CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
  7. NM_007656.5NP_031682.1  CD82 antigen

    See identical proteins and their annotated locations for NP_031682.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the predominant transcript. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
    Source sequence(s)
    AL732483
    Consensus CDS
    CCDS16454.1
    UniProtKB/Swiss-Prot
    P40237
    UniProtKB/TrEMBL
    Q3UII2
    Related
    ENSMUSP00000028644.5, ENSMUST00000028644.11
    Conserved Domains (1) summary
    cd03160
    Location:106228
    CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    93249447..93293295 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)