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Cd79a CD79A antigen (immunoglobulin-associated alpha) [ Mus musculus (house mouse) ]

Gene ID: 12518, updated on 5-Aug-2018
Official Symbol
Cd79aprovided by MGI
Official Full Name
CD79A antigen (immunoglobulin-associated alpha)provided by MGI
Primary source
MGI:MGI:101774
See related
Ensembl:ENSMUSG00000003379 Vega:OTTMUSG00000029270
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Iga; Ly54; mb-1; Ly-54; Igalpha; Ig-alpha
Expression
Biased expression in spleen adult (RPKM 536.2), mammary gland adult (RPKM 128.1) and 1 other tissue See more
Orthologs
See Cd79a in Genome Data Viewer
Location:
7 A3; 7 13.49 cM
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (24897511..24902197)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (25682530..25687216)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene doublesex and mab-3 related transcription factor like family C2 Neighboring gene predicted gene, 38966 Neighboring gene ribosomal protein S19 Neighboring gene Rho guanine nucleotide exchange factor (GEF) 1 Neighboring gene predicted gene 4881

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
B cell activation IMP
Inferred from Mutant Phenotype
more info
PubMed 
B cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
B cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
B cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
B cell receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
B cell receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
immune system process IEA
Inferred from Electronic Annotation
more info
 
protein homotetramerization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
B cell receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
B cell receptor complex IDA
Inferred from Direct Assay
more info
PubMed 
external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
multivesicular body IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
B-cell antigen receptor complex-associated protein alpha chain
Names
MB-1 membrane glycoprotein
membrane-bound immunoglobulin-associated protein
surface IgM-associated protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007655.4NP_031681.2  B-cell antigen receptor complex-associated protein alpha chain precursor

    See identical proteins and their annotated locations for NP_031681.2

    Status: VALIDATED

    Source sequence(s)
    AK143605, BB842272
    Consensus CDS
    CCDS20967.1
    UniProtKB/Swiss-Prot
    P11911
    Related
    ENSMUSP00000003469.7, OTTMUSP00000037360, ENSMUST00000003469.7
    Conserved Domains (3) summary
    smart00077
    Location:179199
    ITAM; Immunoreceptor tyrosine-based activation motif
    smart00410
    Location:35119
    IG_like; Immunoglobulin like
    pfam00047
    Location:35103
    ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

    Range
    24897511..24902197
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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