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ZFP3 ZFP3 zinc finger protein [ Homo sapiens (human) ]

Gene ID: 124961, updated on 11-Jun-2021

Summary

Official Symbol
ZFP3provided by HGNC
Official Full Name
ZFP3 zinc finger proteinprovided by HGNC
Primary source
HGNC:HGNC:12861
See related
Ensembl:ENSG00000180787 MIM:194480
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF752
Expression
Ubiquitous expression in thyroid (RPKM 4.0), duodenum (RPKM 3.8) and 24 other tissues See more
Orthologs
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Genomic context

See ZFP3 in Genome Data Viewer
Location:
17p13.2
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (5078467..5096374)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (4981762..4999669)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 9431 Neighboring gene zinc finger with KRAB and SCAN domains 1 pseudogene Neighboring gene ZNF232 antisense RNA 1 Neighboring gene zinc finger protein 232 Neighboring gene ubiquitin specific peptidase 6 Neighboring gene zinc finger protein 594

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ30726

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 3 homolog
Names
zfp-3
zinc finger protein 752
zinc finger protein homologous to Zfp-3 in mouse
zinc finger protein-3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153018.3NP_694563.1  zinc finger protein 3 homolog

    See identical proteins and their annotated locations for NP_694563.1

    Status: VALIDATED

    Source sequence(s)
    AC012146, BP250703, BX647638
    Consensus CDS
    CCDS11067.1
    UniProtKB/Swiss-Prot
    Q96NJ6
    Related
    ENSP00000320347.3, ENST00000318833.4
    Conserved Domains (2) summary
    COG5048
    Location:139495
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:199219
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    5078467..5096374
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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