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LSM12 LSM12 homolog [ Homo sapiens (human) ]

Gene ID: 124801, updated on 6-Sep-2022

Summary

Official Symbol
LSM12provided by HGNC
Official Full Name
LSM12 homologprovided by HGNC
Primary source
HGNC:HGNC:26407
See related
Ensembl:ENSG00000161654 MIM:611793; AllianceGenome:HGNC:26407
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PNAS-135
Expression
Ubiquitous expression in testis (RPKM 15.2), placenta (RPKM 11.4) and 25 other tissues See more
Orthologs
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Genomic context

See LSM12 in Genome Data Viewer
Location:
17q21.31
Exon count:
8
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (44034328..44067587, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (44886845..44920099, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (42111696..42144955, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene transmembrane protein 101 Neighboring gene small nucleolar RNA U3 Neighboring gene glucose-6-phosphatase catalytic subunit 3 Neighboring gene histone deacetylase 5 Neighboring gene Sharpr-MPRA regulatory region 9416

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp120 env HIV-1 gp120 is identified to have a physical interaction with LSM12 homolog (LSM12) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses PubMed
Pr55(Gag) gag Interaction of HIV-1 Gag with LSM12 homolog (LSM12) is identified in a series of six affinity purification/mass spectrometry screens PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ30656, MGC104211

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
protein LSM12
Names
protein LSM12 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001369484.1NP_001356413.1  protein LSM12 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC023855
    UniProtKB/TrEMBL
    K7ELG9
    Related
    ENSP00000466074.1, ENST00000585388.2
    Conserved Domains (2) summary
    cd01735
    Location:767
    LSm12_N; Like-Sm protein 12, N-terminal domain
    smart00995
    Location:78165
    AD; Anticodon-binding domain
  2. NM_001369485.1NP_001356414.1  protein LSM12 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC023855
    Conserved Domains (2) summary
    cd01735
    Location:767
    LSm12_N; Like-Sm protein 12, N-terminal domain
    smart00995
    Location:78197
    AD; Anticodon-binding domain
  3. NM_001369486.1NP_001356415.1  protein LSM12 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC023855
    Conserved Domains (2) summary
    smart00995
    Location:28107
    AD; Anticodon-binding domain
    cl00259
    Location:728
    Sm_like; Sm and related proteins
  4. NM_001371445.1NP_001358374.1  protein LSM12 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC023855, AL832076, DR762377, HY010534
    UniProtKB/Swiss-Prot
    Q96NL5
    Related
    ENSP00000293406.3, ENST00000293406.8
    Conserved Domains (2) summary
    cd01735
    Location:767
    LSm12_N; Like-Sm protein 12, N-terminal domain
    smart00995
    Location:78165
    AD; Anticodon-binding domain
  5. NM_152344.4NP_689557.1  protein LSM12 isoform 3

    See identical proteins and their annotated locations for NP_689557.1

    Status: VALIDATED

    Source sequence(s)
    AC023855
    Consensus CDS
    CCDS11475.1
    UniProtKB/Swiss-Prot
    Q3MHD2, Q96NL5
    Related
    ENSP00000466718.1, ENST00000591247.6
    Conserved Domains (2) summary
    cd01735
    Location:767
    LSm12_N; Like-Sm protein 12, N-terminal domain
    smart00995
    Location:78165
    AD; Anticodon-binding domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    44034328..44067587 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    44886845..44920099 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)