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Cd151 CD151 antigen [ Mus musculus (house mouse) ]

Gene ID: 12476, updated on 8-Feb-2024

Summary

Official Symbol
Cd151provided by MGI
Official Full Name
CD151 antigenprovided by MGI
Primary source
MGI:MGI:1096360
See related
Ensembl:ENSMUSG00000025510 AllianceGenome:MGI:1096360
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SFA-1; PETA-3; Tspan24
Summary
Predicted to enable integrin binding activity. Acts upstream of or within T cell proliferation and cell migration. Predicted to be located in basement membrane and cell surface. Predicted to be integral component of plasma membrane. Orthologous to human CD151 (CD151 molecule (Raph blood group)). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in adrenal adult (RPKM 306.7), ovary adult (RPKM 269.4) and 22 other tissues See more
Orthologs
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Genomic context

See Cd151 in Genome Data Viewer
Location:
7 F5; 7 86.82 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (141047275..141051394)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (141467362..141471481)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9305 Neighboring gene patatin-like phospholipase domain containing 2 Neighboring gene calcium release activated channel regulator 2B Neighboring gene predicted gene 10575 Neighboring gene polymerase (RNA) II (DNA directed) polypeptide L Neighboring gene STARR-positive B cell enhancer ABC_E11377 Neighboring gene tetraspanin 4 Neighboring gene chitinase domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (5)  1 citation
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables integrin binding ISO
Inferred from Sequence Orthology
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in basement membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cell surface ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
CD151 antigen
Names
GP27
membrane glycoprotein SFA-1
platelet-endothelial tetraspan antigen 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001111049.1NP_001104519.1  CD151 antigen

    See identical proteins and their annotated locations for NP_001104519.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AI155754, AW539552, BQ896459, DV063036, U89772
    Consensus CDS
    CCDS22017.1
    UniProtKB/Swiss-Prot
    O35566, O89118
    UniProtKB/TrEMBL
    Q921J7
    Related
    ENSMUSP00000136331.2, ENSMUST00000177840.9
    Conserved Domains (2) summary
    cd03155
    Location:112220
    CD151_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
    pfam00335
    Location:15248
    Tetraspannin; Tetraspanin family
  2. NM_001111050.1NP_001104520.1  CD151 antigen

    See identical proteins and their annotated locations for NP_001104520.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AI155754, AW539552, CJ066904, U89772
    Consensus CDS
    CCDS22017.1
    UniProtKB/Swiss-Prot
    O35566, O89118
    UniProtKB/TrEMBL
    Q921J7
    Related
    ENSMUSP00000061636.6, ENSMUST00000058746.7
    Conserved Domains (2) summary
    cd03155
    Location:112220
    CD151_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
    pfam00335
    Location:15248
    Tetraspannin; Tetraspanin family
  3. NM_009842.3NP_033972.2  CD151 antigen

    See identical proteins and their annotated locations for NP_033972.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
    Source sequence(s)
    AI155754, AW539552, BQ896459, D89290, U89772
    Consensus CDS
    CCDS22017.1
    UniProtKB/Swiss-Prot
    O35566, O89118
    UniProtKB/TrEMBL
    Q921J7
    Related
    ENSMUSP00000101622.3, ENSMUST00000106000.10
    Conserved Domains (2) summary
    cd03155
    Location:112220
    CD151_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
    pfam00335
    Location:15248
    Tetraspannin; Tetraspanin family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    141047275..141051394
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)