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KIF19 kinesin family member 19 [ Homo sapiens (human) ]

Gene ID: 124602, updated on 2-Mar-2021

Summary

Official Symbol
KIF19provided by HGNC
Official Full Name
kinesin family member 19provided by HGNC
Primary source
HGNC:HGNC:26735
See related
Ensembl:ENSG00000196169
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KIF19A
Expression
Broad expression in spleen (RPKM 3.3), duodenum (RPKM 1.5) and 14 other tissues See more
Orthologs
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Genomic context

See KIF19 in Genome Data Viewer
Location:
17q25.1
Exon count:
20
Annotation release Status Assembly Chr Location
109.20210226 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (74326212..74355820)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (72322365..72351959)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene tweety family member 2 Neighboring gene dynein axonemal intermediate chain 2 Neighboring gene uncharacterized LOC105371891 Neighboring gene uncharacterized LOC107985078 Neighboring gene BTB domain containing 17 Neighboring gene G protein-coupled receptor 142

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ37300

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATP-dependent microtubule motor activity, plus-end-directed IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATP-dependent microtubule motor activity, plus-end-directed ISS
Inferred from Sequence or Structural Similarity
more info
 
ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule motor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
axonemal microtubule depolymerization ISS
Inferred from Sequence or Structural Similarity
more info
 
microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plus-end specific microtubule depolymerization ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
axoneme IEA
Inferred from Electronic Annotation
more info
 
cilium ISS
Inferred from Sequence or Structural Similarity
more info
 
kinesin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153209.4NP_694941.2  kinesin-like protein KIF19

    See identical proteins and their annotated locations for NP_694941.2

    Status: VALIDATED

    Source sequence(s)
    AA527573, AC103809, AW014742, AW339468, BC110989, BE219924, DA955730
    Consensus CDS
    CCDS32718.2
    UniProtKB/Swiss-Prot
    Q2TAC6
    Related
    ENSP00000374566.4, ENST00000389916.5
    Conserved Domains (2) summary
    smart00129
    Location:14353
    KISc; Kinesin motor, catalytic domain. ATPase
    cd01370
    Location:11346
    KISc_KIP3_like; Kinesin motor domain, KIP3-like subgroup

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210226

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    74326212..74355820
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017024150.1XP_016879639.1  kinesin-like protein KIF19 isoform X1

  2. XM_017024151.1XP_016879640.1  kinesin-like protein KIF19 isoform X2

  3. XM_005257029.1XP_005257086.1  kinesin-like protein KIF19 isoform X3

    Conserved Domains (2) summary
    smart00129
    Location:14353
    KISc; Kinesin motor, catalytic domain. ATPase
    cd01370
    Location:11346
    KISc_KIP3_like; Kinesin motor domain, KIP3-like subgroup
  4. XM_017024155.1XP_016879644.1  kinesin-like protein KIF19 isoform X8

  5. XM_017024156.1XP_016879645.1  kinesin-like protein KIF19 isoform X9

  6. XM_017024152.1XP_016879641.1  kinesin-like protein KIF19 isoform X4

  7. XM_017024153.1XP_016879642.1  kinesin-like protein KIF19 isoform X5

  8. XM_005257030.1XP_005257087.1  kinesin-like protein KIF19 isoform X6

    Conserved Domains (2) summary
    smart00129
    Location:14311
    KISc; Kinesin motor, catalytic domain. ATPase
    cd01370
    Location:11304
    KISc_KIP3_like; Kinesin motor domain, KIP3-like subgroup
  9. XM_017024154.1XP_016879643.1  kinesin-like protein KIF19 isoform X7

  10. XM_017024157.1XP_016879646.1  kinesin-like protein KIF19 isoform X10

  11. XM_017024158.1XP_016879647.1  kinesin-like protein KIF19 isoform X11

RNA

  1. XR_001752426.1 RNA Sequence

  2. XR_001752425.1 RNA Sequence

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