U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ccng2 cyclin G2 [ Mus musculus (house mouse) ]

Gene ID: 12452, updated on 27-Nov-2024

Summary

Official Symbol
Ccng2provided by MGI
Official Full Name
cyclin G2provided by MGI
Primary source
MGI:MGI:1095734
See related
Ensembl:ENSMUSG00000029385 AllianceGenome:MGI:1095734
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Acts upstream of or within regulation of cell cycle. Predicted to be located in cytosol. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including cerebral cortex; lung; and tibialis anterior. Orthologous to human CCNG2 (cyclin G2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in CNS E14 (RPKM 30.5), whole brain E14.5 (RPKM 26.3) and 27 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Ccng2 in Genome Data Viewer
Location:
5 E2; 5 47.29 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (93415432..93424090)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (93267573..93276231)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2010109A12 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:93635715-93635902 Neighboring gene predicted gene, 42116 Neighboring gene STARR-positive B cell enhancer ABC_E2751 Neighboring gene CapStarr-seq enhancers MGSCv37_chr5:93695909-93696110 and MGSCv37_chr5:93696229-93696412 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:93696423-93696610 Neighboring gene STARR-seq mESC enhancer starr_13669 Neighboring gene STARR-seq mESC enhancer starr_13670 Neighboring gene predicted gene, 54293 Neighboring gene K(lysine) acetyltransferase 2B, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 
  • Targeted (1)  1 citation

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC113793

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of cell cycle IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of cyclin-dependent protein kinase holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007635.4NP_031661.3  cyclin-G2

    See identical proteins and their annotated locations for NP_031661.3

    Status: VALIDATED

    Source sequence(s)
    AK168891, BC088980, BE957050, BY065574
    Consensus CDS
    CCDS19437.1
    UniProtKB/Swiss-Prot
    O08918, O35612
    UniProtKB/TrEMBL
    Q3TCL9, Q3TG40, Q5HZK4, Q8C9K5
    Related
    ENSMUSP00000031331.7, ENSMUST00000031331.13
    Conserved Domains (1) summary
    pfam00134
    Location:74153
    Cyclin_N; Cyclin, N-terminal domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    93415432..93424090
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)