U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ccnb2 cyclin B2 [ Mus musculus (house mouse) ]

Gene ID: 12442, updated on 17-Jan-2023

Summary

Official Symbol
Ccnb2provided by MGI
Official Full Name
cyclin B2provided by MGI
Primary source
MGI:MGI:88311
See related
Ensembl:ENSMUSG00000032218 AllianceGenome:MGI:88311
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CycB2
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Acts upstream of or within several processes, including T cell homeostasis; meiosis I cell cycle process; and thymus development. Located in cytoplasm and membrane. Is expressed in several structures, including blastocyst; central nervous system; early embryo; gonad; and placenta. Orthologous to human CCNB2 (cyclin B2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in liver E14.5 (RPKM 72.5), liver E14 (RPKM 70.4) and 15 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Ccnb2 in Genome Data Viewer
Location:
9; 9 D
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (70314971..70328836, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (70407689..70421554, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene myosin IE Neighboring gene predicted gene, 18017 Neighboring gene microRNA 5626 Neighboring gene ring finger 111 Neighboring gene predicted gene, 24615 Neighboring gene predicted gene, 23730

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
part_of cyclin-dependent protein kinase holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
G2/mitotic-specific cyclin-B2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007630.2NP_031656.2  G2/mitotic-specific cyclin-B2

    See identical proteins and their annotated locations for NP_031656.2

    Status: VALIDATED

    Source sequence(s)
    AA033463, AK076122, BY300844
    Consensus CDS
    CCDS23320.1
    UniProtKB/Swiss-Prot
    P30276, Q922E9
    Related
    ENSMUSP00000034742.7, ENSMUST00000034742.8
    Conserved Domains (2) summary
    pfam00134
    Location:137262
    Cyclin_N; Cyclin, N-terminal domain
    pfam02984
    Location:264382
    Cyclin_C; Cyclin, C-terminal domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    70314971..70328836 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)