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CDYL2 chromodomain Y like 2 [ Homo sapiens (human) ]

Gene ID: 124359, updated on 26-Sep-2021

Summary

Official Symbol
CDYL2provided by HGNC
Official Full Name
chromodomain Y like 2provided by HGNC
Primary source
HGNC:HGNC:23030
See related
Ensembl:ENSG00000166446 MIM:618816
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PCCP1
Expression
Broad expression in testis (RPKM 6.1), placenta (RPKM 3.9) and 20 other tissues See more
Orthologs
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Genomic context

See CDYL2 in Genome Data Viewer
Location:
16q23.2
Exon count:
10
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (80597899..80805043, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (80631804..80838495, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene DYNLRB2 antisense RNA 1 Neighboring gene uncharacterized LOC105371360 Neighboring gene long intergenic non-protein coding RNA 1227 Neighboring gene androgen receptor regulated long noncoding RNA 1 Neighboring gene C-X9-C motif containing 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide association study of smoking behaviours among Bangladeshi adults.
GeneReviews: Not available
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ38866

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables methylated histone binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
chromodomain Y-like protein 2
Names
CDY-like 2
chromodomain protein, Y-like 2
prostate cancer candidate protein 1, PCCP1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152342.4NP_689555.2  chromodomain Y-like protein 2

    See identical proteins and their annotated locations for NP_689555.2

    Status: VALIDATED

    Source sequence(s)
    AC009070, AC092332, AK096185, AW297969, BC100803, BX390259
    Consensus CDS
    CCDS32493.1
    UniProtKB/Swiss-Prot
    Q8N8U2
    Related
    ENSP00000476295.1, ENST00000570137.7
    Conserved Domains (2) summary
    cd06558
    Location:252448
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
    smart00298
    Location:755
    CHROMO; Chromatin organization modifier domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    80597899..80805043 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011522866.1XP_011521168.1  chromodomain Y-like protein 2 isoform X1

    Conserved Domains (2) summary
    cd06558
    Location:286482
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
    smart00298
    Location:4089
    CHROMO; Chromatin organization modifier domain
  2. XM_011522867.2XP_011521169.1  chromodomain Y-like protein 2 isoform X2

    Conserved Domains (2) summary
    cd06558
    Location:249445
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
    smart00298
    Location:652
    CHROMO; Chromatin organization modifier domain
  3. XM_024450151.1XP_024305919.1  chromodomain Y-like protein 2 isoform X3

    Conserved Domains (1) summary
    cd06558
    Location:193389
    crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
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