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ZG16B zymogen granule protein 16B [ Homo sapiens (human) ]

Gene ID: 124220, updated on 3-May-2024

Summary

Official Symbol
ZG16Bprovided by HGNC
Official Full Name
zymogen granule protein 16Bprovided by HGNC
Primary source
HGNC:HGNC:30456
See related
Ensembl:ENSG00000162078 MIM:620477; AllianceGenome:HGNC:30456
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EECP; PAUF; JCLN2; HRPE773; PRO1567
Summary
Predicted to enable carbohydrate binding activity. Involved in retina homeostasis. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward salivary gland (RPKM 15006.7) See more
Orthologs
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Genomic context

See ZG16B in Genome Data Viewer
Location:
16p13.3
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (2830303..2832276)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (2850876..2852849)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (2880304..2882277)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7074 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7075 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:2870033-2870534 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:2870535-2871034 Neighboring gene serine protease 21 Neighboring gene eukaryotic translation initiation factor 1 pseudogene 4 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr16:2885634-2886833 Neighboring gene uncharacterized LOC124903628 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:2892359-2893048 Neighboring gene serine protease 30, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:2902227-2902726 Neighboring gene serine protease 22 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:2907556-2908156 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:2908157-2908757

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
pancreatic adenocarcinoma up-regulated factor; zymogen granule protein 16 homolog B
Names
endocrine and exocrine protein
jacalin-like lectin domain containing 2
pancreatic adenocarcinoma upregulated factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145252.3NP_660295.3  pancreatic adenocarcinoma up-regulated factor precursor

    Status: VALIDATED

    Source sequence(s)
    AC005361
    Consensus CDS
    CCDS10479.3
    UniProtKB/Swiss-Prot
    A6NIY1, B2R4F6, C3PTT6, Q6UW28, Q96DA0
    UniProtKB/TrEMBL
    A0A0C4DGN4, A0A0U1RQZ6
    Related
    ENSP00000371715.4, ENST00000382280.8
    Conserved Domains (1) summary
    cd09611
    Location:21148
    Jacalin_ZG16_like; Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    2830303..2832276
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_013171812.1 Reference GRCh38.p14 PATCHES

    Range
    5439..11741
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054331877.1XP_054187852.1  zymogen granule protein 16 homolog B isoform X1

    UniProtKB/TrEMBL
    G8H6I3

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    2850876..2852849
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)