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SPATA33 spermatogenesis associated 33 [ Homo sapiens (human) ]

Gene ID: 124045, updated on 1-Jun-2020

Summary

Official Symbol
SPATA33provided by HGNC
Official Full Name
spermatogenesis associated 33provided by HGNC
Primary source
HGNC:HGNC:26463
See related
Ensembl:ENSG00000167523 MIM:615409
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C16orf55
Expression
Broad expression in testis (RPKM 13.1), brain (RPKM 1.9) and 15 other tissues See more
Orthologs

Genomic context

See SPATA33 in Genome Data Viewer
Location:
16q24.3
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (89657744..89671272)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (89724152..89736866)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene dipeptidase 1 Neighboring gene charged multivesicular body protein 1A Neighboring gene long intergenic non-protein coding RNA 2166 Neighboring gene cyclin dependent kinase 10

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association study in Han Chinese identifies three novel loci for human height.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ31606

Gene Ontology Provided by GOA

Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
spermatogenesis-associated protein 33

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271907.1NP_001258836.1  spermatogenesis-associated protein 33 isoform a

    See identical proteins and their annotated locations for NP_001258836.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a).
    Source sequence(s)
    AK303024, BU741532, DB452323, DC374690
    Consensus CDS
    CCDS62012.1
    UniProtKB/Swiss-Prot
    Q96N06
    Related
    ENSP00000462996.1, ENST00000579310.5
    Conserved Domains (1) summary
    pfam15382
    Location:71137
    DUF4609; Domain of unknown function (DUF4609)
  2. NM_001271908.1NP_001258837.1  spermatogenesis-associated protein 33 isoform c

    See identical proteins and their annotated locations for NP_001258837.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Variants 3 and 4 both encode the same isoform (c).
    Source sequence(s)
    AC010538, AK303024, BU741532, DA300380, DB025192
    Consensus CDS
    CCDS73929.1
    UniProtKB/Swiss-Prot
    Q96N06
    UniProtKB/TrEMBL
    A0A087WYH0
    Conserved Domains (1) summary
    pfam15382
    Location:40106
    DUF4609; Domain of unknown function (DUF4609)
  3. NM_001271909.1NP_001258838.1  spermatogenesis-associated protein 33 isoform c

    See identical proteins and their annotated locations for NP_001258838.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Variants 3 and 4 both encode the same isoform (c).
    Source sequence(s)
    AC010538, AK303024, BP345094, BU741532, DB025192, KF459565
    Consensus CDS
    CCDS73929.1
    UniProtKB/Swiss-Prot
    Q96N06
    UniProtKB/TrEMBL
    A0A087WYH0
    Related
    ENSP00000481797.1, ENST00000611218.1
    Conserved Domains (1) summary
    pfam15382
    Location:40106
    DUF4609; Domain of unknown function (DUF4609)
  4. NM_001271910.1NP_001258839.1  spermatogenesis-associated protein 33 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) uses an alternate splice junction at the 5' end of the last exon compared to variant 1, that causes a frameshift. The resulting isoform (d) has a shorter and distinct C-terminus compared to isoform a.
    Source sequence(s)
    AK303024, BU741532, DB452323, DC357681
    UniProtKB/Swiss-Prot
    Q96N06
  5. NM_153025.2NP_694570.1  spermatogenesis-associated protein 33 isoform b

    See identical proteins and their annotated locations for NP_694570.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus compared to isoform a.
    Source sequence(s)
    AK303024, BU741532, DB025192
    Consensus CDS
    CCDS10983.1
    UniProtKB/Swiss-Prot
    Q96N06
    Related
    ENSP00000301031.4, ENST00000301031.8
    Conserved Domains (1) summary
    pfam15382
    Location:70136
    DUF4609; Domain of unknown function (DUF4609)

RNA

  1. NR_073515.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' end compared to variant 1. There is no potential ORF of any reasonable size, so this is thought to be a non-protein coding transcript.
    Source sequence(s)
    AC010538, KF459565
    Related
    ENST00000565890.1
  2. NR_073516.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' and 3' ends compared to variant 1. There is no potential ORF of any reasonable size, so this is thought to be a non-protein coding transcript.
    Source sequence(s)
    AC010538, BP345094, BQ575829, CB216379, KF459565
    Related
    ENST00000568929.1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    89657744..89671272
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006721133.2XP_006721196.1  spermatogenesis-associated protein 33 isoform X1

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