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Calb1 calbindin 1 [ Mus musculus (house mouse) ]

Gene ID: 12307, updated on 14-Jan-2020

Summary

Official Symbol
Calb1provided by MGI
Official Full Name
calbindin 1provided by MGI
Primary source
MGI:MGI:88248
See related
Ensembl:ENSMUSG00000028222
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CB; Calb; Calb-1; Brain-2
Expression
Biased expression in cerebellum adult (RPKM 80.7), kidney adult (RPKM 24.9) and 5 other tissues See more
Orthologs

Genomic context

See Calb1 in Genome Data Viewer
Location:
4 A2; 4 6.66 cM
Exon count:
11
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (15881264..15906709)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (15808411..15833856)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene predicted gene 11857 Neighboring gene mutS homolog 6 pseudogene Neighboring gene small nucleolar RNA SNORA17 Neighboring gene 2,4-dienoyl CoA reductase 1, mitochondrial Neighboring gene microRNA 6400

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 
cellular response to organic substance IDA
Inferred from Direct Assay
more info
PubMed 
locomotory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
long-term memory ISO
Inferred from Sequence Orthology
more info
 
metanephric collecting duct development IEP
Inferred from Expression Pattern
more info
PubMed 
metanephric connecting tubule development IEP
Inferred from Expression Pattern
more info
PubMed 
metanephric distal convoluted tubule development IEP
Inferred from Expression Pattern
more info
PubMed 
metanephric part of ureteric bud development IEP
Inferred from Expression Pattern
more info
PubMed 
regulation of long-term synaptic potentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of long-term synaptic potentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of presynaptic cytosolic calcium ion concentration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of presynaptic cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
 
regulation of synaptic plasticity ISO
Inferred from Sequence Orthology
more info
 
retina development in camera-type eye IEP
Inferred from Expression Pattern
more info
PubMed 
retina layer formation IEP
Inferred from Expression Pattern
more info
PubMed 
short-term memory ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
GABA-ergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
axon IDA
Inferred from Direct Assay
more info
PubMed 
axon ISO
Inferred from Sequence Orthology
more info
 
calyx of Held ISO
Inferred from Sequence Orthology
more info
 
cell body IDA
Inferred from Direct Assay
more info
PubMed 
cuticular plate ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendrite IDA
Inferred from Direct Assay
more info
PubMed 
dendrite ISO
Inferred from Sequence Orthology
more info
 
dendritic spine IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendritic spine ISO
Inferred from Sequence Orthology
more info
 
glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
hippocampal mossy fiber to CA3 synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
intracellular IDA
Inferred from Direct Assay
more info
PubMed 
neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuron projection IDA
Inferred from Direct Assay
more info
PubMed 
neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
postsynapse ISO
Inferred from Sequence Orthology
more info
 
postsynaptic cytosol ISO
Inferred from Sequence Orthology
more info
 
presynaptic cytosol ISO
Inferred from Sequence Orthology
more info
 
stereocilium ISO
Inferred from Sequence Orthology
more info
 
synapse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
calbindin
Names
CalbindinD28K
D-28K
PCD-29
calbindin 1, 28kDa
calbindin D28
calbindin-28K
calbindin-D (28k)
spot 35 protein
vitamin D-dependent calcium-binding protein, avian-type

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009788.4NP_033918.1  calbindin

    See identical proteins and their annotated locations for NP_033918.1

    Status: VALIDATED

    Source sequence(s)
    AK038856, AK048517, BB668373
    Consensus CDS
    CCDS17984.1
    UniProtKB/Swiss-Prot
    P12658
    Related
    ENSMUSP00000029876.1, ENSMUST00000029876.1
    Conserved Domains (2) summary
    cd15902
    Location:1644
    EFh_HEF; EF-hand motif [structural motif]
    cl23634
    Location:16259
    EFh_HEF; EF-hand, calcium binding motif, found in the hexa-EF hand proteins family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p6 C57BL/6J

    Range
    15881264..15906709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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