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Cab39 calcium binding protein 39 [ Mus musculus (house mouse) ]

Gene ID: 12283, updated on 21-May-2024

Summary

Official Symbol
Cab39provided by MGI
Official Full Name
calcium binding protein 39provided by MGI
Primary source
MGI:MGI:107438
See related
Ensembl:ENSMUSG00000036707 AllianceGenome:MGI:107438
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MO25; MO25alpha
Summary
Predicted to enable calcium ion binding activity; kinase binding activity; and protein serine/threonine kinase activator activity. Acts upstream of or within activation of protein kinase activity. Predicted to be located in cytosol and membrane. Predicted to be part of protein-containing complex. Predicted to colocalize with Z disc. Is expressed in several structures, including clavicle; cranial ganglion; dorsal root ganglion; neural retina; and secondary oocyte. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human CAB39 (calcium binding protein 39). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 37.9), colon adult (RPKM 29.2) and 28 other tissues See more
Orthologs
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Genomic context

See Cab39 in Genome Data Viewer
Location:
1 C5; 1 43.94 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (85707796..85779298)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (85793441..85851577)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A630001G21 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:87629249-87629446 Neighboring gene STARR-positive B cell enhancer ABC_E1551 Neighboring gene STARR-positive B cell enhancer ABC_E1999 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:87647325-87647478 Neighboring gene STARR-seq mESC enhancer starr_01553 Neighboring gene microRNA 8096 Neighboring gene RIKEN cDNA 9930111H07 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:87690750-87690933 Neighboring gene STARR-positive B cell enhancer ABC_E3285 Neighboring gene STARR-seq mESC enhancer starr_01556 Neighboring gene integral membrane protein 2C Neighboring gene predicted gene, 32302 Neighboring gene predicted gene, 51745

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium ion binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein kinase activator activity ISO
Inferred from Sequence Orthology
more info
 
enables protein serine/threonine kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein serine/threonine kinase activator activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
colocalizes_with Z disc ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IC
Inferred by Curator
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
part_of serine/threonine protein kinase complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
calcium-binding protein 39
Names
calcium binding protein, 39 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355046.2NP_001341975.1  calcium-binding protein 39 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
    Consensus CDS
    CCDS15112.1
    UniProtKB/Swiss-Prot
    Q06138, Q8VDZ8
    Conserved Domains (1) summary
    pfam08569
    Location:5334
    Mo25; Mo25-like
  2. NM_001355047.2NP_001341976.1  calcium-binding protein 39 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
    Consensus CDS
    CCDS15112.1
    UniProtKB/Swiss-Prot
    Q06138, Q8VDZ8
    Conserved Domains (1) summary
    pfam08569
    Location:5334
    Mo25; Mo25-like
  3. NM_001420006.1NP_001406935.1  calcium-binding protein 39 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
    UniProtKB/Swiss-Prot
    Q06138, Q8VDZ8
    Related
    ENSMUSP00000095270.3, ENSMUST00000097666.4
  4. NM_001420007.1NP_001406936.1  calcium-binding protein 39 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
    UniProtKB/Swiss-Prot
    Q06138, Q8VDZ8
  5. NM_001420009.1NP_001406938.1  calcium-binding protein 39 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
    UniProtKB/Swiss-Prot
    Q06138, Q8VDZ8
  6. NM_001420010.1NP_001406939.1  calcium-binding protein 39 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
    UniProtKB/Swiss-Prot
    Q06138, Q8VDZ8
  7. NM_001420011.1NP_001406940.1  calcium-binding protein 39 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
    UniProtKB/Swiss-Prot
    Q06138, Q8VDZ8
  8. NM_001420012.1NP_001406941.1  calcium-binding protein 39 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
    UniProtKB/Swiss-Prot
    Q06138, Q8VDZ8
  9. NM_001420013.1NP_001406942.1  calcium-binding protein 39 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
    UniProtKB/Swiss-Prot
    Q06138, Q8VDZ8
  10. NM_001420014.1NP_001406943.1  calcium-binding protein 39 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
    UniProtKB/Swiss-Prot
    Q06138, Q8VDZ8
  11. NM_001420015.1NP_001406944.1  calcium-binding protein 39 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
    UniProtKB/Swiss-Prot
    Q06138, Q8VDZ8
  12. NM_001420016.1NP_001406945.1  calcium-binding protein 39 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
  13. NM_001420017.1NP_001406946.1  calcium-binding protein 39 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
  14. NM_001420018.1NP_001406947.1  calcium-binding protein 39 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
  15. NM_001420019.1NP_001406948.1  calcium-binding protein 39 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
  16. NM_001420020.1NP_001406949.1  calcium-binding protein 39 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
  17. NM_001420021.1NP_001406950.1  calcium-binding protein 39 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
  18. NM_001420022.1NP_001406951.1  calcium-binding protein 39 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
  19. NM_133781.6NP_598542.3  calcium-binding protein 39 isoform 1

    See identical proteins and their annotated locations for NP_598542.3

    Status: VALIDATED

    Source sequence(s)
    AC107707, AC161342
    Consensus CDS
    CCDS15112.1
    UniProtKB/Swiss-Prot
    Q06138, Q8VDZ8
    Related
    ENSMUSP00000108987.2, ENSMUST00000113360.8
    Conserved Domains (1) summary
    pfam08569
    Location:5334
    Mo25; Mo25-like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    85707796..85779298
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)