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Btg1 BTG anti-proliferation factor 1 [ Mus musculus (house mouse) ]

Gene ID: 12226, updated on 26-Sep-2022

Summary

Official Symbol
Btg1provided by MGI
Official Full Name
BTG anti-proliferation factor 1provided by MGI
Primary source
MGI:MGI:88215
See related
Ensembl:ENSMUSG00000036478 AllianceGenome:MGI:88215
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable enzyme binding activity. Acts upstream of or within negative regulation of cell population proliferation and protein methylation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including branchial arch; central nervous system; limb; maxillary process; and sensory organ. Orthologous to human BTG1 (BTG anti-proliferation factor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in spleen adult (RPKM 18.3), bladder adult (RPKM 12.4) and 28 other tissues See more
Orthologs
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Genomic context

See Btg1 in Genome Data Viewer
Location:
10; 10 C3
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (96452863..96458675)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (96617001..96622813)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 33843 Neighboring gene VISTA enhancer mm313 Neighboring gene predicted gene, 33897

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein BTG1
Names
B cell translocation gene 1, anti-proliferative
B-cell translocation gene 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007569.2NP_031595.1  protein BTG1

    See identical proteins and their annotated locations for NP_031595.1

    Status: VALIDATED

    Source sequence(s)
    AC155936
    Consensus CDS
    CCDS24140.1
    UniProtKB/Swiss-Prot
    P62325
    UniProtKB/TrEMBL
    A0A6P5QH76, A0A8C6HBE6, Q3UEG0
    Related
    ENSMUSP00000038863.8, ENSMUST00000038377.9
    Conserved Domains (1) summary
    smart00099
    Location:11118
    btg1; tob/btg1 family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    96452863..96458675
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)