Format

Send to:

Choose Destination

Bsn bassoon [ Mus musculus (house mouse) ]

Gene ID: 12217, updated on 18-Apr-2019

Summary

Official Symbol
Bsnprovided by MGI
Official Full Name
bassoonprovided by MGI
Primary source
MGI:MGI:1277955
See related
Ensembl:ENSMUSG00000032589
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Broad expression in cortex adult (RPKM 15.2), frontal lobe adult (RPKM 14.2) and 16 other tissues See more
Orthologs

Genomic context

See Bsn in Genome Data Viewer
Location:
9 F1; 9 59.07 cM
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (108096022..108190419, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (107998353..108092714, complement)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene microRNA 7088 Neighboring gene macrophage stimulating 1 (hepatocyte growth factor-like) Neighboring gene acylpeptide hydrolase Neighboring gene predicted gene, 46132 Neighboring gene RIKEN cDNA 4930447F24 gene Neighboring gene dystroglycan 1 Neighboring gene nicolin 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
dynein light chain binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
structural constituent of presynaptic active zone EXP
Inferred from Experiment
more info
PubMed 
structural constituent of presynaptic active zone IDA
Inferred from Direct Assay
more info
PubMed 
structural constituent of presynaptic active zone IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription corepressor binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
axo-dendritic transport ISO
Inferred from Sequence Orthology
more info
 
presynapse to nucleus signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
presynaptic active zone assembly ISO
Inferred from Sequence Orthology
more info
 
protein localization to synapse IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of synaptic vesicle cycle IDA
Inferred from Direct Assay
more info
PubMed 
regulation of synaptic vesicle cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of ubiquitin protein ligase activity ISO
Inferred from Sequence Orthology
more info
 
retrograde axonal transport ISO
Inferred from Sequence Orthology
more info
 
synapse assembly IEA
Inferred from Electronic Annotation
more info
 
synapse organization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
GABA-ergic synapse EXP
Inferred from Experiment
more info
PubMed 
GABA-ergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
GABA-ergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
GABA-ergic synapse ISO
Inferred from Sequence Orthology
more info
 
Golgi-associated vesicle ISO
Inferred from Sequence Orthology
more info
 
Schaffer collateral - CA1 synapse EXP
Inferred from Experiment
more info
PubMed 
Schaffer collateral - CA1 synapse IDA
Inferred from Direct Assay
more info
PubMed 
Schaffer collateral - CA1 synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
axon IDA
Inferred from Direct Assay
more info
PubMed 
axon cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cell junction IEA
Inferred from Electronic Annotation
more info
 
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton of presynaptic active zone ISO
Inferred from Sequence Orthology
more info
 
dendrite IDA
Inferred from Direct Assay
more info
PubMed 
excitatory synapse ISO
Inferred from Sequence Orthology
more info
 
extrinsic component of membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
glutamatergic synapse EXP
Inferred from Experiment
more info
PubMed 
glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
hippocampal mossy fiber to CA3 synapse ISO
Inferred from Sequence Orthology
more info
 
inhibitory synapse ISO
Inferred from Sequence Orthology
more info
 
NOT integral component of membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
neuron projection IEA
Inferred from Electronic Annotation
more info
 
neuron projection terminus IDA
Inferred from Direct Assay
more info
PubMed 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
piccolo-bassoon transport vesicle ISO
Inferred from Sequence Orthology
more info
 
postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
presynapse IDA
Inferred from Direct Assay
more info
PubMed 
presynaptic active zone IDA
Inferred from Direct Assay
more info
PubMed 
presynaptic active zone ISO
Inferred from Sequence Orthology
more info
PubMed 
presynaptic active zone cytoplasmic component IDA
Inferred from Direct Assay
more info
PubMed 
presynaptic active zone cytoplasmic component ISO
Inferred from Sequence Orthology
more info
 
ribbon synapse ISO
Inferred from Sequence Orthology
more info
 
synapse IDA
Inferred from Direct Assay
more info
PubMed 
synapse ISO
Inferred from Sequence Orthology
more info
PubMed 
colocalizes_with synaptic membrane ISO
Inferred from Sequence Orthology
more info
 
synaptic vesicle ISO
Inferred from Sequence Orthology
more info
 
trans-Golgi network ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein bassoon
Names
presynaptic cytomatrix protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007567.2NP_031593.2  protein bassoon

    See identical proteins and their annotated locations for NP_031593.2

    Status: VALIDATED

    Source sequence(s)
    AC137678, AI836567, AK129141, AK135719, BY742476
    Consensus CDS
    CCDS23517.1
    UniProtKB/Swiss-Prot
    O88737
    UniProtKB/TrEMBL
    Q3UXD6
    Related
    ENSMUSP00000035208.6, ENSMUST00000035208.13
    Conserved Domains (3) summary
    cd15772
    Location:462525
    FYVE2_BSN_PCLO; FYVE-related domain 2 found in protein bassoon and piccolo
    cd15773
    Location:162225
    FYVE1_BSN; FYVE-related domain 1 found in protein bassoon
    pfam10310
    Location:558645
    DUF2413; Protein of unknown function (DUF2413)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

    Range
    108096022..108190419 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511634.3XP_006511697.1  protein bassoon isoform X1

    See identical proteins and their annotated locations for XP_006511697.1

    UniProtKB/Swiss-Prot
    O88737
    Conserved Domains (3) summary
    cd15772
    Location:462525
    FYVE2_BSN_PCLO; FYVE-related domain 2 found in protein bassoon and piccolo
    cd15773
    Location:162225
    FYVE1_BSN; FYVE-related domain 1 found in protein bassoon
    pfam10310
    Location:558645
    DUF2413; Protein of unknown function (DUF2413)
Support Center