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OR10AD1 olfactory receptor family 10 subfamily AD member 1 [ Homo sapiens (human) ]

Gene ID: 121275, updated on 11-Jun-2021

Summary

Official Symbol
OR10AD1provided by HGNC
Official Full Name
olfactory receptor family 10 subfamily AD member 1provided by HGNC
Primary source
HGNC:HGNC:14819
See related
Ensembl:ENSG00000172640
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR12-1; OR10AD1P
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR10AD1 in Genome Data Viewer
Location:
12q13.11
Exon count:
1
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (48202339..48203292, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (48596122..48597075, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene endoplasmic reticulum oxidoreductase 1 alpha pseudogene Neighboring gene coiled-coil domain containing 184 Neighboring gene uncharacterized LOC102725258 Neighboring gene uncharacterized LOC105369753 Neighboring gene H1.7 linker histone

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 10AD1
Names
olfactory receptor OR12-1
olfactory receptor, family 10, subfamily AD, member 1 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004134.1NP_001004134.1  olfactory receptor 10AD1

    See identical proteins and their annotated locations for NP_001004134.1

    Status: PROVISIONAL

    Source sequence(s)
    AB065872
    Consensus CDS
    CCDS31787.1
    UniProtKB/Swiss-Prot
    Q8NGE0
    Related
    ENSP00000308689.2, ENST00000310248.4
    Conserved Domains (2) summary
    pfam00001
    Location:42291
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:35306
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    48202339..48203292 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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