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TMEM52B transmembrane protein 52B [ Homo sapiens (human) ]

Gene ID: 120939, updated on 2-Jul-2020

Summary

Official Symbol
TMEM52Bprovided by HGNC
Official Full Name
transmembrane protein 52Bprovided by HGNC
Primary source
HGNC:HGNC:26438
See related
Ensembl:ENSG00000165685
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C12orf59
Expression
Restricted expression toward kidney (RPKM 46.9) See more
Orthologs

Genomic context

See TMEM52B in Genome Data Viewer
Location:
12p13.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (10170599..10191804)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (10331557..10344403)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369655 Neighboring gene heterogeneous nuclear ribonucleoprotein A/B pseudogene 1 Neighboring gene C-type lectin domain containing 7A Neighboring gene oxidized low density lipoprotein receptor 1 Neighboring gene uncharacterized LOC107984509 Neighboring gene GABA type A receptor associated protein like 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ31166, MGC111385

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
extracellular exosome HDA PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079815.2NP_001073283.1  transmembrane protein 52B isoform 2 precursor

    See identical proteins and their annotated locations for NP_001073283.1

    Status: VALIDATED

    Source sequence(s)
    AC024224, AC115676
    Consensus CDS
    CCDS66314.1
    UniProtKB/Swiss-Prot
    Q4KMG9
    Related
    ENSP00000371348.2, ENST00000381923.6
    Conserved Domains (1) summary
    pfam14979
    Location:33161
    TMEM52; Transmembrane 52
  2. NM_001384894.1NP_001371823.1  transmembrane protein 52B isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC024224, AC115676
  3. NM_001384895.1NP_001371824.1  transmembrane protein 52B isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC024224, AC115676
  4. NM_001384896.1NP_001371825.1  transmembrane protein 52B isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC115676
  5. NM_001384897.1NP_001371826.1  transmembrane protein 52B isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AC115676
  6. NM_001384898.1NP_001371827.1  transmembrane protein 52B isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC024224, AC115676
  7. NM_153022.4NP_694567.1  transmembrane protein 52B isoform 1

    See identical proteins and their annotated locations for NP_694567.1

    Status: VALIDATED

    Source sequence(s)
    AC115676, AY358845, BE301029
    Consensus CDS
    CCDS8619.1
    UniProtKB/Swiss-Prot
    Q4KMG9
    Related
    ENSP00000298530.3, ENST00000298530.7
    Conserved Domains (1) summary
    pfam14979
    Location:13141
    TMEM52; Transmembrane 52

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    10170599..10191804
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006719029.3XP_006719092.1  transmembrane protein 52B isoform X1

    UniProtKB/Swiss-Prot
    Q4KMG9
    Conserved Domains (1) summary
    pfam14979
    Location:33161
    TMEM52; Transmembrane 52
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