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OR2D3 olfactory receptor family 2 subfamily D member 3 [ Homo sapiens (human) ]

Gene ID: 120775, updated on 22-Sep-2022

Summary

Official Symbol
OR2D3provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily D member 3provided by HGNC
Primary source
HGNC:HGNC:15146
See related
Ensembl:ENSG00000178358 AllianceGenome:HGNC:15146
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-89
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR2D3 in Genome Data Viewer
Location:
11p15.4
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (6921002..6921994)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (6979425..6980417)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (6942233..6943225)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 10 subfamily A member 4 Neighboring gene uncharacterized LOC107984019 Neighboring gene olfactory receptor family 2 subfamily D member 2 Neighboring gene zinc finger protein 215 Neighboring gene uncharacterized LOC102724711 Neighboring gene Sharpr-MPRA regulatory region 9308

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 2D3
Names
olfactory receptor OR11-89

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004684.1NP_001004684.1  olfactory receptor 2D3

    See identical proteins and their annotated locations for NP_001004684.1

    Status: VALIDATED

    Source sequence(s)
    BK004294
    Consensus CDS
    CCDS31417.1
    UniProtKB/Swiss-Prot
    Q8NGH3, Q96R51
    Related
    ENSP00000320560.3, ENST00000317834.5
    Conserved Domains (1) summary
    cd15428
    Location:54317
    7tmA_OR2D-like; olfactory receptor subfamily 2D and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    6921002..6921994
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    6979425..6980417
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)