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ROCK1 Rho associated coiled-coil containing protein kinase 1 [ Pteropus giganteus (Indian flying fox) ]

Gene ID: 120587763, updated on 30-Mar-2024

Summary

Gene symbol
ROCK1
Gene description
Rho associated coiled-coil containing protein kinase 1
See related
EnsemblRapid:ENSPGIG00000002106
Gene type
protein coding
RefSeq status
MODEL
Organism
Pteropus giganteus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
Orthologs
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Genomic context

Location:
chromosome: Un
Exon count:
33
Annotation release Status Assembly Chr Location
100 current Ma_sr-lr_union100 (GCF_902729225.1) Unplaced Scaffold NW_024340849.1 (39986557..40114895)

NW_024340849.1Genomic Context describing neighboring genes Neighboring gene proteolipid protein 2-like Neighboring gene 5S ribosomal RNA Neighboring gene 5S ribosomal RNA Neighboring gene ubiquitin specific peptidase 14 Neighboring gene uncharacterized LOC120587867 Neighboring gene THO complex 1 Neighboring gene collectin subfamily member 12

Genomic regions, transcripts, and products

Genomic Sequence:
NW_024340849 Unplaced Scaffold Reference Ma_sr-lr_union100

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables Rho-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in actomyosin structure organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cortical actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in embryonic morphogenesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in peptidyl-threonine phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of cell junction assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasmic stress granule IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
rho-associated protein kinase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pteropus giganteus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Ma_sr-lr_union100

Genomic

  1. NW_024340849.1 Reference Ma_sr-lr_union100

    Range
    39986557..40114895
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039844936.1XP_039700870.1  rho-associated protein kinase 1 isoform X1

    Related
    ENSPGIP00000001782.1, ENSPGIT00000002681.1
    Conserved Domains (6) summary
    cd11639
    Location:489554
    HR1_ROCK1; Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rho-associated coiled-coil containing protein kinase 1
    cd01242
    Location:11191225
    PH_ROCK; Rho-associated coiled-coil containing protein kinase pleckstrin homology (PH) domain
    cd05622
    Location:2406
    STKc_ROCK1; Catalytic domain of the Serine/Threonine Kinase, Rho-associated coiled-coil containing protein kinase 1
    TIGR02168
    Location:4261097
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd22250
    Location:836913
    ROCK_SBD; Shroom-binding domain found in Rho-associated coiled-coil containing protein kinase
    cd20874
    Location:12221290
    C1_ROCK1; protein kinase C conserved region 1 (C1 domain) found in Rho-associated coiled-coil containing protein kinase 1 (ROCK1) and similar proteins
  2. XM_039844937.1XP_039700871.1  rho-associated protein kinase 1 isoform X2

    Conserved Domains (6) summary
    cd11639
    Location:488553
    HR1_ROCK1; Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rho-associated coiled-coil containing protein kinase 1
    cd01242
    Location:11181224
    PH_ROCK; Rho-associated coiled-coil containing protein kinase pleckstrin homology (PH) domain
    cd05622
    Location:2406
    STKc_ROCK1; Catalytic domain of the Serine/Threonine Kinase, Rho-associated coiled-coil containing protein kinase 1
    TIGR02168
    Location:4241096
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd22250
    Location:835912
    ROCK_SBD; Shroom-binding domain found in Rho-associated coiled-coil containing protein kinase
    cd20874
    Location:12211289
    C1_ROCK1; protein kinase C conserved region 1 (C1 domain) found in Rho-associated coiled-coil containing protein kinase 1 (ROCK1) and similar proteins