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Bcl7c B cell CLL/lymphoma 7C [ Mus musculus (house mouse) ]

Gene ID: 12055, updated on 3-Jan-2023

Summary

Official Symbol
Bcl7cprovided by MGI
Official Full Name
B cell CLL/lymphoma 7Cprovided by MGI
Primary source
MGI:MGI:1332237
See related
Ensembl:ENSMUSG00000030814 AllianceGenome:MGI:1332237
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C230096E12Rik
Summary
Predicted to act upstream of or within apoptotic process. Is expressed in embryo. Orthologous to human BCL7C (BAF chromatin remodeling complex subunit BCL7C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 8.6), CNS E18 (RPKM 7.8) and 28 other tissues See more
Orthologs
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Genomic context

See Bcl7c in Genome Data Viewer
Location:
7; 7 F3
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (127260626..127307938, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127661454..127708766, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 51458 Neighboring gene predicted gene, 53373 Neighboring gene predicted gene, 39090 Neighboring gene microRNA 762 Neighboring gene cardiotrophin 1 Neighboring gene cardiotrophin 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
part_of GBAF complex NAS
Non-traceable Author Statement
more info
PubMed 
part_of SWI/SNF complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of SWI/SNF complex ISO
Inferred from Sequence Orthology
more info
 
part_of SWI/SNF complex NAS
Non-traceable Author Statement
more info
PubMed 
located_in chromatin NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
B-cell CLL/lymphoma 7 protein family member C
Names
B-cell chronic lymphocytic leukemia/lymphoma 7C protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347652.1NP_001334581.1  B-cell CLL/lymphoma 7 protein family member C isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC124507
    Consensus CDS
    CCDS85422.1
    UniProtKB/TrEMBL
    A0A0U1RNX8
    Related
    ENSMUSP00000145743.2, ENSMUST00000205977.2
  2. NM_009746.2NP_033876.1  B-cell CLL/lymphoma 7 protein family member C isoform 2

    See identical proteins and their annotated locations for NP_033876.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    BC005673
    Consensus CDS
    CCDS21874.1
    UniProtKB/Swiss-Prot
    O08664, Q99LS2
    UniProtKB/TrEMBL
    A0A8C6I0N8
    Related
    ENSMUSP00000057937.9, ENSMUST00000061468.9
    Conserved Domains (2) summary
    PHA03249
    Location:93177
    PHA03249; DNA packaging tegument protein UL25; Provisional
    pfam04714
    Location:450
    BCL_N; BCL7, N-terminal conserver region

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    127260626..127307938 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)