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NXPE2 neurexophilin and PC-esterase domain family member 2 [ Homo sapiens (human) ]

Gene ID: 120406, updated on 23-Nov-2021

Summary

Official Symbol
NXPE2provided by HGNC
Official Full Name
neurexophilin and PC-esterase domain family member 2provided by HGNC
Primary source
HGNC:HGNC:26331
See related
Ensembl:ENSG00000204361
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM55B
Expression
Biased expression in colon (RPKM 2.7), salivary gland (RPKM 0.7) and 2 other tissues See more
Orthologs
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Genomic context

See NXPE2 in Genome Data Viewer
Location:
11q23.2-q23.3
Exon count:
21
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (114464276..114813702)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (114549249..114577791)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene nocturnin pseudogene Neighboring gene RNA exonuclease 2 Neighboring gene histone deacetylase 2 pseudogene Neighboring gene neurexophilin and PC-esterase domain family member 2 pseudogene 1 Neighboring gene neurexophilin and PC-esterase domain family member 1 Neighboring gene uncharacterized LOC105369504 Neighboring gene neurexophilin and PC-esterase domain family member 4 Neighboring gene uncharacterized LOC105369506 Neighboring gene uncharacterized LOC105369505 Neighboring gene cell adhesion molecule 1 Neighboring gene uncharacterized LOC105369509

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25224

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
NXPE family member 2
Names
family with sequence similarity 55, member B
protein FAM55B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_182495.6NP_872301.2  NXPE family member 2

    See identical proteins and their annotated locations for NP_872301.2

    Status: VALIDATED

    Source sequence(s)
    AP002774
    Consensus CDS
    CCDS44738.1
    UniProtKB/Swiss-Prot
    Q96DL1
    Related
    ENSP00000374237.4, ENST00000389586.6
    Conserved Domains (1) summary
    pfam06312
    Location:142274
    Neurexophilin

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    114464276..114813702
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017017209.1XP_016872698.1  NXPE family member 2 isoform X2

    Conserved Domains (1) summary
    pfam06312
    Location:118250
    Neurexophilin; Neurexophilin
  2. XM_017017207.1XP_016872696.1  NXPE family member 2 isoform X2

    Conserved Domains (1) summary
    pfam06312
    Location:118250
    Neurexophilin; Neurexophilin
  3. XM_017017208.1XP_016872697.1  NXPE family member 2 isoform X2

    Conserved Domains (1) summary
    pfam06312
    Location:118250
    Neurexophilin; Neurexophilin
  4. XM_011542604.2XP_011540906.1  NXPE family member 2 isoform X2

    See identical proteins and their annotated locations for XP_011540906.1

    Conserved Domains (1) summary
    pfam06312
    Location:118250
    Neurexophilin; Neurexophilin
  5. XM_017017212.1XP_016872701.1  NXPE family member 2 isoform X4

  6. XM_017017211.1XP_016872700.1  NXPE family member 2 isoform X3

  7. XM_017017206.1XP_016872695.1  NXPE family member 2 isoform X1

RNA

  1. XR_001747769.1 RNA Sequence

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