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DBX1 developing brain homeobox 1 [ Homo sapiens (human) ]

Gene ID: 120237, updated on 13-Mar-2020

Summary

Official Symbol
DBX1provided by HGNC
Official Full Name
developing brain homeobox 1provided by HGNC
Primary source
HGNC:HGNC:33185
See related
Ensembl:ENSG00000109851
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See DBX1 in Genome Data Viewer
Location:
11p15.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (20156155..20160475, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (20177760..20181870, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene neuron navigator 2 Neighboring gene NAV2 antisense RNA 2 Neighboring gene uncharacterized LOC107984418 Neighboring gene uncharacterized LOC105376583 Neighboring gene NFE2L2 motif-containing MPRA enhancer 64 Neighboring gene HIV-1 Tat interactive protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cell differentiation in spinal cord IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ventral spinal cord interneuron specification IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nuclear chromatin ISA
Inferred from Sequence Alignment
more info
 

General protein information

Preferred Names
homeobox protein DBX1
Names
developing brain homeobox protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001029865.4NP_001025036.2  homeobox protein DBX1

    See identical proteins and their annotated locations for NP_001025036.2

    Status: VALIDATED

    Source sequence(s)
    AC068860
    Consensus CDS
    CCDS31443.2
    UniProtKB/Swiss-Prot
    A6NMT0
    Related
    ENSP00000436881.2, ENST00000524983.3
    Conserved Domains (1) summary
    pfam00046
    Location:184237
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    20156155..20160475 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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