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OR4C46 olfactory receptor family 4 subfamily C member 46 [ Homo sapiens (human) ]

Gene ID: 119749, updated on 22-Sep-2022

Summary

Official Symbol
OR4C46provided by HGNC
Official Full Name
olfactory receptor family 4 subfamily C member 46provided by HGNC
Primary source
HGNC:HGNC:31271
See related
Ensembl:ENSG00000185926 MIM:614273; AllianceGenome:HGNC:31271
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR4C46 in Genome Data Viewer
Location:
11q11
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (54603069..54603998, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (54539093..54540022, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (51515282..51516211)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene DExH-box helicase 9 pseudogene Neighboring gene olfactory receptor family 4 subfamily C member 50 pseudogene Neighboring gene olfactory receptor family 4 subfamily C member 7 pseudogene Neighboring gene olfactory receptor family 4 subfamily R member 2 pseudogene

Genomic regions, transcripts, and products

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004703.1NP_001004703.1  olfactory receptor 4C46

    See identical proteins and their annotated locations for NP_001004703.1

    Status: PROVISIONAL

    Source sequence(s)
    AC126345
    Consensus CDS
    CCDS73288.1
    UniProtKB/Swiss-Prot
    A6NHA9
    Related
    ENSP00000329056.1, ENST00000328188.1
    Conserved Domains (2) summary
    pfam00001
    Location:41285
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:29303
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    54603069..54603998 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    54539093..54540022 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)