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PSTK phosphoseryl-tRNA kinase [ Homo sapiens (human) ]

Gene ID: 118672, updated on 23-Nov-2021

Summary

Official Symbol
PSTKprovided by HGNC
Official Full Name
phosphoseryl-tRNA kinaseprovided by HGNC
Primary source
HGNC:HGNC:28578
See related
Ensembl:ENSG00000179988 MIM:611310
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C10orf89
Expression
Ubiquitous expression in bone marrow (RPKM 1.8), testis (RPKM 1.5) and 25 other tissues See more
Orthologs
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Genomic context

See PSTK in Genome Data Viewer
Location:
10q26.13
Exon count:
8
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (122980401..122990390)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (124739917..124749906)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 13232 Neighboring gene family with sequence similarity 24 member A Neighboring gene chromosome 10 open reading frame 88 Neighboring gene IKAROS family zinc finger 5 Neighboring gene acyl-CoA dehydrogenase short/branched chain Neighboring gene Sharpr-MPRA regulatory region 13327

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC35392

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables L-seryl-tRNA(Sec) kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables tRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in selenocysteinyl-tRNA(Sec) biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
L-seryl-tRNA(Sec) kinase
Names
O-phosphoseryl-tRNA(Sec) kinase
NP_001350460.1
NP_699167.2
XP_016871130.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363531.2NP_001350460.1  L-seryl-tRNA(Sec) kinase isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC073585
    Consensus CDS
    CCDS86153.1
    Related
    ENSP00000384653.3, ENST00000406217.8
    Conserved Domains (1) summary
    TIGR03575
    Location:20357
    selen_PSTK_euk; L-seryl-tRNA(Sec) kinase, eukaryotic
  2. NM_153336.3NP_699167.2  L-seryl-tRNA(Sec) kinase isoform 2

    See identical proteins and their annotated locations for NP_699167.2

    Status: VALIDATED

    Source sequence(s)
    AC073585, BC035344
    Consensus CDS
    CCDS7633.1
    UniProtKB/Swiss-Prot
    Q8IV42
    Related
    ENSP00000357882.3, ENST00000368887.7
    Conserved Domains (2) summary
    pfam13671
    Location:20212
    AAA_33; AAA domain
    cl17190
    Location:20301
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    122980401..122990390
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017015641.2XP_016871130.1  L-seryl-tRNA(Sec) kinase isoform X2

RNA

  1. XR_001747018.1 RNA Sequence

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