Bmal1 basic helix-loop-helix ARNT like 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Bmal1provided by MGI
Official Full Name: basic helix-loop-helix ARNT like 1provided by MGI
Primary source: MGI:MGI:1096381
See related: Ensembl:ENSMUSG00000055116 AllianceGenome:MGI:1096381
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: MOP3; Arnt3; Arntl; BMAL1b; bHLHe5; bmal1b'
Summary: The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with Clock. This heterodimer binds E-box enhancer elements upstream of Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2) genes and activates transcription of these genes. Per and Cry proteins heterodimerize and repress their own transcription by interacting in a feedback loop with Clock/Arntl complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014]
Expression: Ubiquitous expression in thymus adult (RPKM 4.9), large intestine adult (RPKM 4.6) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 F1; 7 59.17 cM

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (112777820..112913333)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (113178471..113314126)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Glial Bmal1 role in mammalian retina daily changes.
Title: Glial Bmal1 role in mammalian retina daily changes.
Myeloid deficiency of the intrinsic clock protein BMAL1 accelerates cognitive aging by disrupting microglial synaptic pruning.
Title: Myeloid deficiency of the intrinsic clock protein BMAL1 accelerates cognitive aging by disrupting microglial synaptic pruning.
BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma.
Title: BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma.
Cartilage-specific deficiency of clock gene Bmal1 accelerated articular cartilage degeneration in osteoarthritis by up-regulation of mTORC1 signaling.
Title: Cartilage-specific deficiency of clock gene Bmal1 accelerated articular cartilage degeneration in osteoarthritis by up-regulation of mTORC1 signaling.
Adrenal-Specific KO of the Circadian Clock Protein BMAL1 Alters Blood Pressure Rhythm and Timing of Eating Behavior.
Title: Adrenal-Specific KO of the Circadian Clock Protein BMAL1 Alters Blood Pressure Rhythm and Timing of Eating Behavior.
The Circadian Clock, Nutritional Signals and Reproduction: A Close Relationship.
Title: The Circadian Clock, Nutritional Signals and Reproduction: A Close Relationship.
Circadian disruption in lung fibroblasts enhances NF-kappaB activity to exacerbate neutrophil recruitment.
Title: Circadian disruption in lung fibroblasts enhances NF-κB activity to exacerbate neutrophil recruitment.
Combined physical exercise reverses the reduced expression of Bmal1 in the liver of aged mice.
Title: Combined physical exercise reverses the reduced expression of Bmal1 in the liver of aged mice.
Loss of myeloid Bmal1 exacerbates hypertensive vascular remodelling through interaction with STAT6 in mice.
Title: Loss of myeloid Bmal1 exacerbates hypertensive vascular remodelling through interaction with STAT6 in mice.
Bmal1 Regulates Prostate Growth via Cell-Cycle Modulation.
Title: Bmal1 Regulates Prostate Growth via Cell-Cycle Modulation.

Submit: New GeneRIF Correction See all GeneRIFs (313)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Gene trapped (1)
Targeted (8) 1 citation
Endonuclease-mediated (4)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

G67009 (e-PCR)
- UniSTS:178215

Arntl (e-PCR), detects polymorphism
- UniSTS:545896

UniSTS:224416 (e-PCR)
- UniSTS:224416

NoName (e-PCR)
- UniSTS:235754

Arntl (e-PCR), detects polymorphism
- UniSTS:547569

Homology

Homologs of the Bmal1 gene: The Bmal1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, fruit fly, mosquito, and frog.
Orthologs from Annotation Pipeline: 349 organisms have orthologs with human gene Bmal1
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables DNA binding	IPI Inferred from Physical Interaction more info	PubMed
enables DNA binding	ISO Inferred from Sequence Orthology more info
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IC Inferred by Curator more info	PubMed
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	ISA Inferred from Sequence Alignment more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor binding	ISO Inferred from Sequence Orthology more info
enables E-box binding	IDA Inferred from Direct Assay more info	PubMed
enables E-box binding	ISO Inferred from Sequence Orthology more info
enables Hsp90 protein binding	ISO Inferred from Sequence Orthology more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables aryl hydrocarbon receptor binding	ISO Inferred from Sequence Orthology more info
enables bHLH transcription factor binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info
enables protein heterodimerization activity	IPI Inferred from Physical Interaction more info	PubMed
enables sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables sequence-specific double-stranded DNA binding	ISO Inferred from Sequence Orthology more info
enables transcription cis-regulatory region binding	IDA Inferred from Direct Assay more info	PubMed
enables transcription factor binding	ISA Inferred from Sequence Alignment more info	PubMed

Process	Evidence Code	Pubs
involved_in circadian regulation of gene expression	IDA Inferred from Direct Assay more info	PubMed
involved_in circadian regulation of gene expression	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in circadian regulation of gene expression	ISO Inferred from Sequence Orthology more info
involved_in circadian rhythm	IBA Inferred from Biological aspect of Ancestor more info	PubMed
acts_upstream_of_or_within circadian rhythm	IDA Inferred from Direct Assay more info	PubMed
involved_in circadian rhythm	IDA Inferred from Direct Assay more info	PubMed
involved_in circadian rhythm	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within circadian rhythm	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in maternal process involved in parturition	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of TOR signaling	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of cold-induced thermogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of fat cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of glucocorticoid receptor signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in oxidative stress-induced premature senescence	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of DNA-templated transcription	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of canonical Wnt signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of circadian rhythm	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of circadian rhythm	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of protein acetylation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of protein acetylation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of skeletal muscle cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within protein import into nucleus	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of cellular senescence	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of hair cycle	ISO Inferred from Sequence Orthology more info
involved_in regulation of insulin secretion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of neurogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of protein catabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info	PubMed
involved_in regulation of type B pancreatic cell development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to redox state	IDA Inferred from Direct Assay more info	PubMed
involved_in response to redox state	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within rhythmic process	IEA Inferred from Electronic Annotation more info
involved_in spermatogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of CLOCK-BMAL transcription complex	IPI Inferred from Physical Interaction more info	PubMed
part_of CLOCK-BMAL transcription complex	ISO Inferred from Sequence Orthology more info
part_of aryl hydrocarbon receptor complex	IBA Inferred from Biological aspect of Ancestor more info	PubMed
located_in chromatoid body	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	TAS Traceable Author Statement more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
located_in nuclear body	IDA Inferred from Direct Assay more info	PubMed
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	TAS Traceable Author Statement more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of transcription regulator complex	IDA Inferred from Direct Assay more info	PubMed
part_of transcription regulator complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: basic helix-loop-helix ARNT-like protein 1; aryl hydrocarbon receptor nuclear translocator-like protein 1

Names: brain and muscle ARNT-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001243048.2 → NP_001229977.1 basic helix-loop-helix ARNT-like protein 1 isoform 2

See identical proteins and their annotated locations for NP_001229977.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) lacks several in-frame exons in the coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.

Source sequence(s)

AC156605

Consensus CDS

CCDS85390.1

UniProtKB/Swiss-Prot

Q9WTL8

UniProtKB/TrEMBL

Q3UHZ2

Related

ENSMUSP00000147764.2, ENSMUST00000210074.2

Conserved Domains (3) summary

smart00091
Location:136 → 195

PAS; PAS domain

pfam00010
Location:61 → 113

HLH; Helix-loop-helix DNA-binding domain

cl25986
Location:326 → 428

PAS_3; PAS fold
NM_001357070.2 → NP_001343999.1 basic helix-loop-helix ARNT-like protein 1 isoform 3

Status: VALIDATED

Description

Transcript Variant: This variant (3) uses an alternate, in-frame splice site in the 3' coding region, compared to variant 1, and encodes a shorter isoform (3), compared to isoform 1.

Source sequence(s)

AC156605

UniProtKB/TrEMBL

A0A6P5Q0F8

Conserved Domains (3) summary

smart00091
Location:149 → 208

PAS; PAS domain

cd11438
Location:67 → 130

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins

pfam14598
Location:338 → 440

PAS_11; PAS domain
NM_001368412.1 → NP_001355341.1 basic helix-loop-helix ARNT-like protein 1 isoform 4

Status: VALIDATED

Source sequence(s)

AC156605

UniProtKB/Swiss-Prot

Q9WTL9

UniProtKB/TrEMBL

A0A6P7REZ3

Conserved Domains (3) summary

pfam00989
Location:153 → 260

PAS; PAS fold

pfam14598
Location:345 → 447

PAS_11; PAS domain

cd11438
Location:74 → 137

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins
NM_001374642.1 → NP_001361571.1 basic helix-loop-helix ARNT-like protein 1 isoform 5

Status: VALIDATED

Source sequence(s)

AC156605

Consensus CDS

CCDS90314.1

UniProtKB/TrEMBL

A0A1B0GS77, A0A6P7R7U9

Related

ENSMUSP00000147823.2, ENSMUST00000211770.2

Conserved Domains (3) summary

pfam00989
Location:153 → 260

PAS; PAS fold

pfam14598
Location:346 → 448

PAS_11; PAS domain

cd11438
Location:74 → 137

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins
NM_001411976.1 → NP_001398905.1 basic helix-loop-helix ARNT-like protein 1 isoform 6

Status: VALIDATED

Description

Transcript Variant: This variant (6) encodes the longest isoform (6).

Source sequence(s)

AC156605
NM_001411977.1 → NP_001398906.1 basic helix-loop-helix ARNT-like protein 1 isoform 5

Status: VALIDATED

Source sequence(s)

AC156605

UniProtKB/TrEMBL

A0A1B0GS77, A0A6P7R7U9
NM_001411978.1 → NP_001398907.1 basic helix-loop-helix ARNT-like protein 1 isoform 7

Status: VALIDATED

Source sequence(s)

AC156605
NM_001411979.1 → NP_001398908.1 basic helix-loop-helix ARNT-like protein 1 isoform 1

Status: VALIDATED

Source sequence(s)

AC156605

UniProtKB/TrEMBL

A0A6P5PXN8, Q3UHZ2
NM_001411980.1 → NP_001398909.1 basic helix-loop-helix ARNT-like protein 1 isoform 1

Status: VALIDATED

Source sequence(s)

AC156605

UniProtKB/TrEMBL

A0A6P5PXN8, Q3UHZ2
NM_001411981.1 → NP_001398910.1 basic helix-loop-helix ARNT-like protein 1 isoform 3

Status: VALIDATED

Source sequence(s)

AC156605

UniProtKB/TrEMBL

A0A6P5Q0F8
NM_007489.5 → NP_031515.1 basic helix-loop-helix ARNT-like protein 1 isoform 1

See identical proteins and their annotated locations for NP_031515.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) encodes isoform 1.

Source sequence(s)

AC156605

Consensus CDS

CCDS40092.1

UniProtKB/Swiss-Prot

Q9WTL8

UniProtKB/TrEMBL

A0A6P5PXN8, Q3UHZ2

Related

ENSMUSP00000046235.8, ENSMUST00000047321.9

Conserved Domains (3) summary

pfam00989
Location:146 → 253

PAS; PAS fold

pfam14598
Location:339 → 441

PAS_11; PAS domain

cd11438
Location:67 → 130

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins

RNA

NR_177990.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC156605
NR_177991.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC156605

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

112777820..112913333

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006507246.5 → XP_006507309.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1

See identical proteins and their annotated locations for XP_006507309.1

Conserved Domains (3) summary

pfam00989
Location:153 → 260

PAS; PAS fold

pfam14598
Location:346 → 448

PAS_11; PAS domain

cd11438
Location:74 → 137

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins
XM_006507245.4 → XP_006507308.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1

See identical proteins and their annotated locations for XP_006507308.1

Conserved Domains (3) summary

pfam00989
Location:153 → 260

PAS; PAS fold

pfam14598
Location:346 → 448

PAS_11; PAS domain

cd11438
Location:74 → 137

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins
XM_006507249.4 → XP_006507312.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X2

Conserved Domains (3) summary

pfam00989
Location:153 → 260

PAS; PAS fold

pfam14598
Location:345 → 447

PAS_11; PAS domain

cd11438
Location:74 → 137

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins
XM_036152605.1 → XP_036008498.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X7

Conserved Domains (1) summary

pfam14598
Location:89 → 191

PAS_11; PAS domain
XM_036152606.1 → XP_036008499.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X8

Conserved Domains (1) summary

pfam14598
Location:88 → 190

PAS_11; PAS domain
XM_006507252.4 → XP_006507315.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X3

Conserved Domains (3) summary

smart00091
Location:149 → 208

PAS; PAS domain

cd11438
Location:67 → 130

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins

pfam14598
Location:339 → 441

PAS_11; PAS domain
XM_006507253.4 → XP_006507316.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X4

Conserved Domains (3) summary

pfam00989
Location:146 → 253

PAS; PAS fold

pfam14598
Location:338 → 440

PAS_11; PAS domain

cd11438
Location:67 → 130

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins
XM_011241656.4 → XP_011239958.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1

See identical proteins and their annotated locations for XP_011239958.1

Conserved Domains (3) summary

pfam00989
Location:153 → 260

PAS; PAS fold

pfam14598
Location:346 → 448

PAS_11; PAS domain

cd11438
Location:74 → 137

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins
XM_030242018.2 → XP_030097878.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X3

Conserved Domains (3) summary

smart00091
Location:149 → 208

PAS; PAS domain

cd11438
Location:67 → 130

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins

pfam14598
Location:339 → 441

PAS_11; PAS domain
XM_006507248.4 → XP_006507311.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1

Conserved Domains (3) summary

pfam00989
Location:153 → 260

PAS; PAS fold

pfam14598
Location:346 → 448

PAS_11; PAS domain

cd11438
Location:74 → 137

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins
XM_030242020.1 → XP_030097880.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X6

Conserved Domains (3) summary

smart00091
Location:149 → 208

PAS; PAS domain

cd11438
Location:67 → 130

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins

pfam14598
Location:338 → 440

PAS_11; PAS domain
XM_030242019.1 → XP_030097879.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5

Conserved Domains (3) summary

pfam00989
Location:146 → 253

PAS; PAS fold

pfam14598
Location:339 → 441

PAS_11; PAS domain

cd11438
Location:67 → 130

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins
XM_036152604.1 → XP_036008497.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X3

Conserved Domains (3) summary

smart00091
Location:149 → 208

PAS; PAS domain

cd11438
Location:67 → 130

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins

pfam14598
Location:339 → 441

PAS_11; PAS domain
XM_006507247.5 → XP_006507310.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X1

See identical proteins and their annotated locations for XP_006507310.1

Conserved Domains (3) summary

pfam00989
Location:153 → 260

PAS; PAS fold

pfam14598
Location:346 → 448

PAS_11; PAS domain

cd11438
Location:74 → 137

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins
XM_017321950.2 → XP_017177439.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X6

UniProtKB/Swiss-Prot

Q9WTL8

UniProtKB/TrEMBL

A0A6P5Q0F8

Conserved Domains (3) summary

smart00091
Location:149 → 208

PAS; PAS domain

cd11438
Location:67 → 130

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins

pfam14598
Location:338 → 440

PAS_11; PAS domain
XM_030242022.2 → XP_030097882.1 aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X9

Conserved Domains (3) summary

pfam00989
Location:129 → 236

PAS; PAS fold

pfam14598
Location:322 → 424

PAS_11; PAS domain

cd11438
Location:50 → 113

bHLH-PAS_ARNTL_PASD3; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) and similar proteins