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hopAB2 type III secretion system effector E3 ubiquitin-protein ligase HopAB2 [ Pseudomonas syringae pv. tomato str. DC3000 ]

Gene ID: 1184744, updated on 10-Feb-2026
Gene symbol
hopAB2
Gene description
type III secretion system effector E3 ubiquitin-protein ligase HopAB2
Locus tag
PSPTO_RS15965
Gene type
protein coding
Organism
Pseudomonas syringae pv. tomato str. DC3000 (strain: DC3000, pathovar: tomato, type-material: reference strain of Pseudomonas syringae group genomosp. 3)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
Old locus tag
PSPTO3087; PSPTO_3087
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Sequence:
NC_004578.1 (3468470..3470131, complement)

NC_004578.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene helix-turn-helix domain-containing protein Neighboring gene ABC transporter substrate-binding protein Neighboring gene ABC transporter permease Neighboring gene ABC transporter permease Neighboring gene dipeptide ABC transporter ATP-binding protein

Genomic Sequence:
NC_004578.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A bacterial inhibitor of host programmed cell death defenses is an E3 ubiquitin ligase. Janjusevic R, et al. Science, 2006 Jan 13. PMID 16373536
  2. Pseudomonas syringae pv. tomato type III effectors AvrPto and AvrPtoB promote ethylene-dependent cell death in tomato. Cohn JR, et al. Plant J, 2005 Oct. PMID 16167902
  3. Pseudomonas type III effector AvrPtoB induces plant disease susceptibility by inhibition of host programmed cell death. Abramovitch RB, et al. EMBO J, 2003 Jan 2. PMID 12505984, Free PMC Article
  4. Genomewide identification of Pseudomonas syringae pv. tomato DC3000 promoters controlled by the HrpL alternative sigma factor. Fouts DE, et al. Proc Natl Acad Sci U S A, 2002 Feb 19. PMID 11854524, Free PMC Article
  5. Phosphorylation of the Pseudomonas Effector AvrPtoB by Arabidopsis SnRK2.8 Is Required for Bacterial Virulence. Lei L, et al. Mol Plant, 2020 Oct 5. PMID 32889173, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Phosphorylation of the Pseudomonas Effector AvrPtoB by Arabidopsis SnRK2.8 Is Required for Bacterial Virulence.
    Title: Phosphorylation of the Pseudomonas Effector AvrPtoB by Arabidopsis SnRK2.8 Is Required for Bacterial Virulence.
  2. This work uncovers a strategy in which Pseudomonas syringae AvrPtoB targets Arabidopsis NPR1 and represses NPR1-dependent salicylic acid signaling, thereby subverting plant innate immunity.
    Title: A Bacterial Type III Effector Targets the Master Regulator of Salicylic Acid Signaling, NPR1, to Subvert Plant Immunity.
  3. we propose that both domains of Pseudomonas syringae pv tomato DC3000 AvrPtoB act together to support the virulence of PtoDC3000 in Arabidopsis through their ability to eliminate FLS2 from the cell periphery.
    Title: Plant pattern-recognition receptor FLS2 is directed for degradation by the bacterial ubiquitin ligase AvrPtoB.
  4. AvrPto and AvrPtoB have phenotypically redundant avirulence activity on Pto-expressing tomato and additive virulence activities on susceptible tomato plants.
    Title: An avrPto/avrPtoB mutant of Pseudomonas syringae pv. tomato DC3000 does not elicit Pto-mediated resistance and is less virulent on tomato.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Preferred Names
type III secretion system effector E3 ubiquitin-protein ligase HopAB2

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004578.1 Reference assembly

    Range
    3468470..3470131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_011104378.1 type III secretion system effector E3 ubiquitin-protein ligase HopAB2

    See identical proteins and their annotated locations for WP_011104378.1

    UniProtKB/Swiss-Prot
    Q7C4D6, Q8RSY1
    Conserved Domains (3) summary
    cd12802
    Location:124 → 202
    HopAB_PID; Pto-interacting domain of the HopAB family of Type III Effector proteins
    pfam09046
    Location:436 → 553
    AvrPtoB-E3_ubiq; AvrPtoB E3 ubiquitin ligase
    pfam16847
    Location:266 → 356
    AvrPtoB_bdg; Avirulence AvrPtoB, BAK1-binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8RSY1.1

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