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Baalc brain and acute leukemia, cytoplasmic [ Mus musculus (house mouse) ]

Gene ID: 118452, updated on 5-Mar-2024

Summary

Official Symbol
Baalcprovided by MGI
Official Full Name
brain and acute leukemia, cytoplasmicprovided by MGI
Primary source
MGI:MGI:1928704
See related
Ensembl:ENSMUSG00000022296 AllianceGenome:MGI:1928704
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810457D07Rik
Summary
Located in cytoplasm. Is expressed in central nervous system and retina. Orthologous to human BAALC (BAALC binder of MAP3K1 and KLF4). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in frontal lobe adult (RPKM 33.0), cortex adult (RPKM 32.4) and 3 other tissues See more
Orthologs
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Genomic context

Location:
15 B3.1; 15 15.18 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (38739763..38814659)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (38933909..38951264)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 45924 Neighboring gene predicted gene, 53229 Neighboring gene predicted gene, 53878 Neighboring gene STARR-seq mESC enhancer starr_38467 Neighboring gene STARR-seq mESC enhancer starr_38469 Neighboring gene predicted gene, 33123 Neighboring gene ATPase family, AAA domain containing 3A pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (2) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in sarcoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
brain and acute leukemia cytoplasmic protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080640.6NP_542371.1  brain and acute leukemia cytoplasmic protein isoform 1-6-8

    See identical proteins and their annotated locations for NP_542371.1

    Status: VALIDATED

    Source sequence(s)
    AC164883, FO082315
    UniProtKB/Swiss-Prot
    A9JR49, Q8VBS8, Q8VHV1, Q9CYS9
    Related
    ENSMUSP00000154447.3, ENSMUST00000226440.3
    Conserved Domains (1) summary
    pfam06989
    Location:149
    BAALC_N; BAALC N-terminus

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    38739763..38814659
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159094.1XP_036014987.1  brain and acute leukemia cytoplasmic protein isoform X3

    Related
    ENSMUSP00000159442.2, ENSMUST00000239553.1
    Conserved Domains (1) summary
    pfam06989
    Location:150
    BAALC_N; BAALC N-terminus
  2. XM_036159093.1XP_036014986.1  brain and acute leukemia cytoplasmic protein isoform X2

    Conserved Domains (1) summary
    pfam06989
    Location:150
    BAALC_N; BAALC N-terminus
  3. XM_036159092.1XP_036014985.1  brain and acute leukemia cytoplasmic protein isoform X1

    Related
    ENSMUSP00000132788.2, ENSMUST00000163313.3