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Mrps2 mitochondrial ribosomal protein S2 [ Mus musculus (house mouse) ]

Gene ID: 118451, updated on 2-Oct-2018

Summary

Official Symbol
Mrps2provided by MGI
Official Full Name
mitochondrial ribosomal protein S2provided by MGI
Primary source
MGI:MGI:2153089
See related
Ensembl:ENSMUSG00000035772 Vega:OTTMUSG00000011644
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1500019M10Rik
Expression
Ubiquitous expression in kidney adult (RPKM 23.2), adrenal adult (RPKM 20.6) and 28 other tissues See more
Orthologs

Genomic context

See Mrps2 in Genome Data Viewer
Location:
2; 2 A3
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (28465956..28471177)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (28323586..28326697)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene predicted gene 13373 Neighboring gene RIKEN cDNA 1700007K13 gene Neighboring gene protein phosphatase 1, regulatory subunit 26 Neighboring gene ribosomal protein SA, pseudogene 9 Neighboring gene globoside alpha-1,3-N-acetylgalactosaminyltransferase 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
mitochondrial ribosome assembly ISO
Inferred from Sequence Orthology
more info
 
mitochondrial translation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
intracellular IEA
Inferred from Electronic Annotation
more info
 
mitochondrial small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
mitochondrial small ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
mitochondrion HDA PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
ribosome IEA
Inferred from Electronic Annotation
more info
 
small ribosomal subunit IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
28S ribosomal protein S2, mitochondrial
Names
MRP-S2
S2mt

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001166031.2NP_001159503.2  28S ribosomal protein S2, mitochondrial isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AK051184, AK077219
    UniProtKB/Swiss-Prot
    Q924T2
    UniProtKB/TrEMBL
    Q8BQ99
    Conserved Domains (1) summary
    cd01425
    Location:62237
    RPS2; Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of ...
  2. NM_080452.3NP_536700.3  28S ribosomal protein S2, mitochondrial isoform 1

    See identical proteins and their annotated locations for NP_536700.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK051184, AK077219
    Consensus CDS
    CCDS15838.1
    UniProtKB/Swiss-Prot
    Q924T2
    UniProtKB/TrEMBL
    Q8BQ99
    Related
    ENSMUSP00000036725.3, OTTMUSP00000012397, ENSMUST00000038600.3, OTTMUST00000027259
    Conserved Domains (1) summary
    cd01425
    Location:81256
    RPS2; Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

    Range
    28465956..28471177
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006497625.2XP_006497688.1  28S ribosomal protein S2, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_006497688.1

    Conserved Domains (1) summary
    cd01425
    Location:127302
    RPS2; Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of ...
  2. XM_011239013.1XP_011237315.1  28S ribosomal protein S2, mitochondrial isoform X2

    Conserved Domains (1) summary
    cd01425
    Location:3160
    RPS2; Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of ...
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