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Apoa4 apolipoprotein A-IV [ Mus musculus (house mouse) ]

Gene ID: 11808, updated on 23-May-2018
Official Symbol
Apoa4provided by MGI
Official Full Name
apolipoprotein A-IVprovided by MGI
Primary source
MGI:MGI:88051
See related
Ensembl:ENSMUSG00000032080 Vega:OTTMUSG00000028705
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Apoa-4
Expression
Biased expression in duodenum adult (RPKM 2830.4), small intestine adult (RPKM 1726.5) and 2 other tissues See more
Orthologs
See Apoa4 in Genome Data Viewer
Location:
9 A5.2; 9 25.36 cM
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (46240844..46243458)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (46048927..46051541)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene apolipoprotein A-I Neighboring gene apolipoprotein C-III Neighboring gene apolipoprotein A-V Neighboring gene ZPR1 zinc finger Neighboring gene BUD13 homolog

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
antioxidant activity ISO
Inferred from Sequence Orthology
more info
 
cholesterol binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cholesterol transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cholesterol transporter activity ISO
Inferred from Sequence Orthology
more info
 
copper ion binding ISO
Inferred from Sequence Orthology
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
lipid binding ISO
Inferred from Sequence Orthology
more info
 
phosphatidylcholine binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylcholine binding ISO
Inferred from Sequence Orthology
more info
 
phosphatidylcholine-sterol O-acyltransferase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylcholine-sterol O-acyltransferase activator activity ISO
Inferred from Sequence Orthology
more info
 
phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cholesterol biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cholesterol efflux IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cholesterol efflux ISO
Inferred from Sequence Orthology
more info
 
cholesterol homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cholesterol homeostasis ISO
Inferred from Sequence Orthology
more info
 
cholesterol metabolic process ISO
Inferred from Sequence Orthology
more info
 
high-density lipoprotein particle assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hydrogen peroxide catabolic process ISO
Inferred from Sequence Orthology
more info
 
innate immune response in mucosa IMP
Inferred from Mutant Phenotype
more info
PubMed 
innate immune response in mucosa ISO
Inferred from Sequence Orthology
more info
 
leukocyte cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
lipid catabolic process ISO
Inferred from Sequence Orthology
more info
 
lipid homeostasis ISO
Inferred from Sequence Orthology
more info
 
lipid transport ISO
Inferred from Sequence Orthology
more info
 
lipoprotein metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of plasma lipoprotein oxidation ISO
Inferred from Sequence Orthology
more info
 
neuron projection regeneration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylcholine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylcholine metabolic process ISO
Inferred from Sequence Orthology
more info
 
phospholipid efflux IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phospholipid efflux ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cholesterol esterification IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of cholesterol esterification ISO
Inferred from Sequence Orthology
more info
 
positive regulation of fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of fatty acid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of lipid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of lipoprotein lipase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of lipoprotein lipase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of triglyceride catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of triglyceride catabolic process ISO
Inferred from Sequence Orthology
more info
 
protein-lipid complex assembly ISO
Inferred from Sequence Orthology
more info
 
regulation of cholesterol transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of cholesterol transport ISO
Inferred from Sequence Orthology
more info
 
regulation of intestinal cholesterol absorption IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of intestinal cholesterol absorption IMP
Inferred from Mutant Phenotype
more info
PubMed 
removal of superoxide radicals ISO
Inferred from Sequence Orthology
more info
 
response to lipid hydroperoxide ISO
Inferred from Sequence Orthology
more info
 
response to stilbenoid IEP
Inferred from Expression Pattern
more info
PubMed 
reverse cholesterol transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
reverse cholesterol transport ISO
Inferred from Sequence Orthology
more info
 
triglyceride catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
triglyceride homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
very-low-density lipoprotein particle remodeling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
very-low-density lipoprotein particle remodeling ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
colocalizes_with cell surface ISO
Inferred from Sequence Orthology
more info
 
chylomicron IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chylomicron ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
high-density lipoprotein particle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
high-density lipoprotein particle ISO
Inferred from Sequence Orthology
more info
 
very-low-density lipoprotein particle ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
apolipoprotein A-IV
Names
apo-AIV
apoA-IV
apolipoprotein A4

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007468.2NP_031494.2  apolipoprotein A-IV precursor

    See identical proteins and their annotated locations for NP_031494.2

    Status: VALIDATED

    Source sequence(s)
    AK168687, BF660098
    Consensus CDS
    CCDS23142.1
    UniProtKB/Swiss-Prot
    P06728
    Related
    ENSMUSP00000034585.6, OTTMUSP00000036353, ENSMUST00000034585.6, OTTMUST00000071089
    Conserved Domains (2) summary
    pfam01442
    Location:66235
    Apolipoprotein; Apolipoprotein A1/A4/E domain
    cl21528
    Location:268368
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

    Range
    46240844..46243458
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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