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Ap3d1 adaptor-related protein complex 3, delta 1 subunit [ Mus musculus (house mouse) ]

Gene ID: 11776, updated on 12-Aug-2019

Summary

Official Symbol
Ap3d1provided by MGI
Official Full Name
adaptor-related protein complex 3, delta 1 subunitprovided by MGI
Primary source
MGI:MGI:107734
See related
Ensembl:ENSMUSG00000020198
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mh; Ap3d; Bolvr; mocha; mBLVR1; AA407035
Expression
Ubiquitous expression in testis adult (RPKM 54.8), ovary adult (RPKM 50.0) and 28 other tissues See more
Orthologs

Genomic context

See Ap3d1 in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
32
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (80706956..80742303, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (80169723..80204956, complement)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene MOB kinase activator 3A Neighboring gene IZUMO family member 4 Neighboring gene DOT1-like, histone H3 methyltransferase (S. cerevisiae) Neighboring gene VISTA enhancer mm200 Neighboring gene pleckstrin homology domain containing, family J member 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Spontaneous (3)  1 citation
  • Targeted (1) 
  • Chemically induced (ENU) (1) 

Pathways from BioSystems

  • Lysosome, organism-specific biosystem (from KEGG)
    Lysosome, organism-specific biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...
  • Lysosome, conserved biosystem (from KEGG)
    Lysosome, conserved biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC140989

Gene Ontology Provided by MGI

Process Evidence Code Pubs
Golgi to vacuole transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
anterograde axonal transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
anterograde synaptic vesicle transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
anterograde synaptic vesicle transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
antigen processing and presentation IMP
Inferred from Mutant Phenotype
more info
PubMed 
antigen processing and presentation, exogenous lipid antigen via MHC class Ib IMP
Inferred from Mutant Phenotype
more info
PubMed 
endosome to melanosome transport ISO
Inferred from Sequence Orthology
more info
 
intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
intracellular protein transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
intracellular protein transport TAS
Traceable Author Statement
more info
PubMed 
neurotransmitter receptor transport, postsynaptic endosome to lysosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neurotransmitter receptor transport, postsynaptic endosome to lysosome IDA
Inferred from Direct Assay
more info
PubMed 
neurotransmitter receptor transport, postsynaptic endosome to lysosome IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of NK T cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein localization to membrane ISO
Inferred from Sequence Orthology
more info
 
protein localization to organelle IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein targeting to vacuole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein transport IEA
Inferred from Electronic Annotation
more info
 
regulation of sequestering of zinc ion ISO
Inferred from Sequence Orthology
more info
 
regulation of sequestering of zinc ion TAS
Traceable Author Statement
more info
PubMed 
synaptic vesicle budding from endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synaptic vesicle budding from endosome IDA
Inferred from Direct Assay
more info
PubMed 
synaptic vesicle budding from endosome IMP
Inferred from Mutant Phenotype
more info
PubMed 
synaptic vesicle budding from endosome ISO
Inferred from Sequence Orthology
more info
 
synaptic vesicle membrane organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synaptic vesicle membrane organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
vesicle-mediated transport TAS
Traceable Author Statement
more info
PubMed 
vesicle-mediated transport in synapse IDA
Inferred from Direct Assay
more info
PubMed 
vesicle-mediated transport in synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
zinc ion transport TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
AP-3 adaptor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
axon IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endosome membrane IDA
Inferred from Direct Assay
more info
PubMed 
endosome membrane ISO
Inferred from Sequence Orthology
more info
 
glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
membrane coat IEA
Inferred from Electronic Annotation
more info
 
postsynapse IDA
Inferred from Direct Assay
more info
PubMed 
presynapse IDA
Inferred from Direct Assay
more info
PubMed 
presynaptic endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
presynaptic endosome IDA
Inferred from Direct Assay
more info
PubMed 
terminal bouton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
terminal bouton IDA
Inferred from Direct Assay
more info
PubMed 
trans-Golgi network TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
AP-3 complex subunit delta-1
Names
AP-3 complex subunit delta
adapter-related protein complex 3 subunit delta-1
adaptor-related protein complex 3 subunit delta-1
adaptor-related protein complex 3, delta subunit
adaptor-related protein complex AP-3, delta subunit
delta-adaptin

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007460.2NP_031486.1  AP-3 complex subunit delta-1

    See identical proteins and their annotated locations for NP_031486.1

    Status: VALIDATED

    Source sequence(s)
    AC152410, BC053066, CJ131283
    Consensus CDS
    CCDS35984.1
    UniProtKB/Swiss-Prot
    O54774
    Related
    ENSMUSP00000020420.7, ENSMUST00000020420.8
    Conserved Domains (4) summary
    pfam01602
    Location:32581
    Adaptin_N; Adaptin N terminal region
    pfam06375
    Location:661803
    BLVR; Bovine leukaemia virus receptor (BLVR)
    pfam12717
    Location:155265
    Cnd1; non-SMC mitotic condensation complex subunit 1
    sd00044
    Location:151172
    HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p6 C57BL/6J

    Range
    80706956..80742303 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030244850.1XP_030100710.1  AP-3 complex subunit delta-1 isoform X1

RNA

  1. XR_003948582.1 RNA Sequence

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