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Anxa7 annexin A7 [ Mus musculus (house mouse) ]

Gene ID: 11750, updated on 21-May-2019

Summary

Official Symbol
Anxa7provided by MGI
Official Full Name
annexin A7provided by MGI
Primary source
MGI:MGI:88031
See related
Ensembl:ENSMUSG00000021814
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Anx7; synexin; AI265384; AI316497
Expression
Ubiquitous expression in placenta adult (RPKM 48.4), bladder adult (RPKM 40.7) and 28 other tissues See more
Orthologs

Genomic context

See Anxa7 in Genome Data Viewer
Location:
14 A3; 14 11.53 cM
Exon count:
14
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (20455261..20480133, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (21274483..21299355, complement)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S16 Neighboring gene cilia and flagella associated protein 70 Neighboring gene MSS51 mitochondrial translational activator Neighboring gene protein phosphatase 3, catalytic subunit, beta isoform Neighboring gene RIKEN cDNA 1810062O18 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
calcium-dependent phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium-dependent phospholipid binding ISO
Inferred from Sequence Orthology
more info
 
calcium-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium-dependent protein binding ISO
Inferred from Sequence Orthology
more info
 
identical protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integrin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integrin binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
autophagy ISO
Inferred from Sequence Orthology
more info
 
cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular calcium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular water homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
epithelial cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hemostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
membrane fusion ISO
Inferred from Sequence Orthology
more info
 
negative regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
regulation of cell shape IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to calcium ion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to calcium ion ISO
Inferred from Sequence Orthology
more info
 
response to organic cyclic compound ISO
Inferred from Sequence Orthology
more info
 
response to salt stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with chromaffin granule membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with chromaffin granule membrane ISO
Inferred from Sequence Orthology
more info
 
collagen-containing extracellular matrix HDA PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
nuclear envelope IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
vesicle IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
annexin A7
Names
annexin VII
annexin-7

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110794.1NP_001104264.1  annexin A7

    See identical proteins and their annotated locations for NP_001104264.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate splice site which results in a shorter 5' UTR, as compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK134589, AK169199, CJ163805
    Consensus CDS
    CCDS26845.1
    UniProtKB/Swiss-Prot
    Q07076
    UniProtKB/TrEMBL
    Q3UYL7
    Related
    ENSMUSP00000066035.9, ENSMUST00000065504.16
    Conserved Domains (1) summary
    pfam00191
    Location:164229
    Annexin; Annexin
  2. NM_009674.3NP_033804.2  annexin A7

    See identical proteins and their annotated locations for NP_033804.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) is the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK032013, AK134589, AK169199, CJ163805
    Consensus CDS
    CCDS26845.1
    UniProtKB/Swiss-Prot
    Q07076
    UniProtKB/TrEMBL
    Q3UYL7, Q8CCV9
    Related
    ENSMUSP00000153669.1, ENSMUST00000224975.1
    Conserved Domains (1) summary
    pfam00191
    Location:164229
    Annexin; Annexin

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

    Range
    20455261..20480133 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006518452.2XP_006518515.1  annexin A7 isoform X1

    See identical proteins and their annotated locations for XP_006518515.1

    UniProtKB/TrEMBL
    A0A2C9F2D2
    Related
    ENSMUSP00000098405.5, ENSMUST00000100844.5
    Conserved Domains (1) summary
    pfam00191
    Location:186251
    Annexin; Annexin
  2. XM_006518453.3XP_006518516.1  annexin A7 isoform X1

    See identical proteins and their annotated locations for XP_006518516.1

    UniProtKB/TrEMBL
    A0A2C9F2D2
    Conserved Domains (1) summary
    pfam00191
    Location:186251
    Annexin; Annexin
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