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Anxa5 annexin A5 [ Mus musculus (house mouse) ]

Gene ID: 11747, updated on 23-Apr-2019

Summary

Official Symbol
Anxa5provided by MGI
Official Full Name
annexin A5provided by MGI
Primary source
MGI:MGI:106008
See related
Ensembl:ENSMUSG00000027712
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Anx5; R74653
Expression
Broad expression in lung adult (RPKM 179.5), adrenal adult (RPKM 154.2) and 27 other tissues See more
Orthologs

Genomic context

See Anxa5 in Genome Data Viewer
Location:
3 B; 3 17.46 cM
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (36448923..36475887, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (36347845..36374809, complement)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 42209 Neighboring gene hemopexin pseudogene Neighboring gene CD164 antigen pseudogene Neighboring gene RIKEN cDNA 1810062G17 gene Neighboring gene microRNA 7009 Neighboring gene predicted gene 11548

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
calcium-dependent phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium-dependent phospholipid binding ISO
Inferred from Sequence Orthology
more info
 
calcium-transporting ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium-transporting ATPase activity ISO
Inferred from Sequence Orthology
more info
 
heparin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peptide hormone binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peptide hormone binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
receptor tyrosine kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
receptor tyrosine kinase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
blood coagulation IEA
Inferred from Electronic Annotation
more info
 
cellular response to gonadotropin-releasing hormone IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to gonadotropin-releasing hormone ISO
Inferred from Sequence Orthology
more info
 
cellular response to lead ion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hemostasis IEA
Inferred from Electronic Annotation
more info
 
negative regulation of blood coagulation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of blood coagulation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of coagulation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of prolactin secretion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of prolactin secretion ISO
Inferred from Sequence Orthology
more info
 
negative regulation of sequestering of calcium ion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
protein homooligomerization ISO
Inferred from Sequence Orthology
more info
 
regulation of flagellated sperm motility IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of flagellated sperm motility ISO
Inferred from Sequence Orthology
more info
 
response to calcium ion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to calcium ion ISO
Inferred from Sequence Orthology
more info
 
response to organic substance IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to organic substance IDA
Inferred from Direct Assay
more info
PubMed 
response to thyroid hormone IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
Z disc ISO
Inferred from Sequence Orthology
more info
 
axon terminus ISO
Inferred from Sequence Orthology
more info
 
cell projection ISO
Inferred from Sequence Orthology
more info
 
collagen-containing extracellular matrix HDA PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
dendrite ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
endothelial microparticle IDA
Inferred from Direct Assay
more info
PubMed 
external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
intercalated disc ISO
Inferred from Sequence Orthology
more info
 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
perikaryon ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
sarcolemma ISO
Inferred from Sequence Orthology
more info
 
synaptic vesicle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
annexin A5
Names
CBP-I
PAP-I
PP4
VAC-alpha
anchorin CII
annexin V
annexin-5
calphobindin I
endonexin II
lipocortin V
placental anticoagulant protein 4
placental anticoagulant protein I
thromboplastin inhibitor
vascular anticoagulant-alpha

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009673.2NP_033803.1  annexin A5

    See identical proteins and their annotated locations for NP_033803.1

    Status: VALIDATED

    Source sequence(s)
    AI845042, AK152185, AK153388, BY297767, CX218962
    Consensus CDS
    CCDS38416.1
    UniProtKB/Swiss-Prot
    P48036
    Related
    ENSMUSP00000029266.8, ENSMUST00000029266.13
    Conserved Domains (1) summary
    pfam00191
    Location:1882
    Annexin; Annexin

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

    Range
    36448923..36475887 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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