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Amy1 amylase 1, salivary [ Mus musculus (house mouse) ]

Gene ID: 11722, updated on 8-Dec-2018

Summary

Official Symbol
Amy1provided by MGI
Official Full Name
amylase 1, salivaryprovided by MGI
Primary source
MGI:MGI:88019
See related
Ensembl:ENSMUSG00000074264
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Amy-1; Amy1a; C030014B17Rik
Expression
Broad expression in liver E18 (RPKM 29.9), CNS E18 (RPKM 24.2) and 17 other tissues See more

Genomic context

See Amy1 in Genome Data Viewer
Location:
3 F3; 3 49.35 cM
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (113555952..113577750, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (113258870..113280668, complement)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene amylase 2a1 Neighboring gene predicted gene, 46820 Neighboring gene RNA-binding region (RNP1, RRM) containing 3 Neighboring gene ribosomal protein L5 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
alpha-amylase activity ISO
Inferred from Sequence Orthology
more info
 
amylase activity IDA
Inferred from Direct Assay
more info
PubMed 
calcium ion binding ISO
Inferred from Sequence Orthology
more info
 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
cation binding IEA
Inferred from Electronic Annotation
more info
 
chloride ion binding ISO
Inferred from Sequence Orthology
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
carbohydrate catabolic process ISO
Inferred from Sequence Orthology
more info
 
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
response to bacterium IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
alpha-amylase 1
Names
1,4-alpha-D-glucan glucanohydrolase 1
salivary and hepatic alpha-amylase
NP_001103975.1
NP_031472.2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110505.1NP_001103975.1  alpha-amylase 1 precursor

    See identical proteins and their annotated locations for NP_001103975.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AA616210, BB462169, CK791844, J00356, V00717, V00720
    Consensus CDS
    CCDS17776.1
    UniProtKB/Swiss-Prot
    P00687
    Related
    ENSMUSP00000070368.5, ENSMUST00000067980.11
    Conserved Domains (3) summary
    cd11317
    Location:25416
    AmyAc_bac_euk_AmyA; Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase)
    smart00632
    Location:422510
    Aamy_C; Aamy_C domain
    COG0366
    Location:46315
    AmyA; Glycosidase [Carbohydrate transport and metabolism]
  2. NM_007446.2NP_031472.2  alpha-amylase 1 precursor

    See identical proteins and their annotated locations for NP_031472.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AA616210, BB462169, CK791844, J00356, V00717, V00719
    Consensus CDS
    CCDS17776.1
    UniProtKB/Swiss-Prot
    P00687
    Related
    ENSMUSP00000102150.1, ENSMUST00000106540.7
    Conserved Domains (3) summary
    cd11317
    Location:25416
    AmyAc_bac_euk_AmyA; Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase)
    smart00632
    Location:422510
    Aamy_C; Aamy_C domain
    COG0366
    Location:46315
    AmyA; Glycosidase [Carbohydrate transport and metabolism]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

    Range
    113555952..113577750 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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