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SCGB3A2 secretoglobin family 3A member 2 [ Homo sapiens (human) ]

Gene ID: 117156, updated on 1-Jun-2020

Summary

Official Symbol
SCGB3A2provided by HGNC
Official Full Name
secretoglobin family 3A member 2provided by HGNC
Primary source
HGNC:HGNC:18391
See related
Ensembl:ENSG00000164265 MIM:606531
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LU103; PNSP1; UGRP1; pnSP-1
Summary
The protein encoded by this gene is a secreted lung surfactant protein and a downstream target of thyroid transcription factor. A single nucleotide polymorphism in the promoter of this gene results in susceptibility to asthma.[provided by RefSeq, Mar 2010]
Expression
Restricted expression toward lung (RPKM 220.9) See more
Orthologs

Genomic context

See SCGB3A2 in Genome Data Viewer
Location:
5q32
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (147878711..147882191)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (147258274..147261756)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene serine peptidase inhibitor Kazal type 1 Neighboring gene formyl peptide receptor 1 pseudogene Neighboring gene chromosome 5 open reading frame 46 Neighboring gene eukaryotic translation elongation factor 1 gamma pseudogene 2 Neighboring gene serine peptidase inhibitor Kazal type 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
receptor-mediated endocytosis TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
endocytic vesicle lumen TAS
Traceable Author Statement
more info
 
extracellular region TAS
Traceable Author Statement
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
secretoglobin family 3A member 2
Names
pneumo secretory protein 1
uteroglobin-related protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016867.1 RefSeqGene

    Range
    5001..8481
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_054023.5NP_473364.1  secretoglobin family 3A member 2 precursor

    See identical proteins and their annotated locations for NP_473364.1

    Status: REVIEWED

    Source sequence(s)
    AA988559, BC024232
    Consensus CDS
    CCDS4287.1
    UniProtKB/Swiss-Prot
    Q96PL1
    UniProtKB/TrEMBL
    Q2L6B3
    Related
    ENSP00000296694.4, ENST00000296694.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    147878711..147882191
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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