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Acsm1 acyl-CoA synthetase medium-chain family member 1 [ Mus musculus (house mouse) ]

Gene ID: 117147, updated on 9-Feb-2019

Summary

Official Symbol
Acsm1provided by MGI
Official Full Name
acyl-CoA synthetase medium-chain family member 1provided by MGI
Primary source
MGI:MGI:2152200
See related
Ensembl:ENSMUSG00000033533
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Macs; Acas3; Bucs1
Expression
Biased expression in liver adult (RPKM 94.8), kidney adult (RPKM 81.4) and 1 other tissue See more
Orthologs

Genomic context

See Acsm1 in Genome Data Viewer
Location:
7; 7 F2
Exon count:
14
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (119617763..119662515)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (126761337..126806029)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene acyl-CoA synthetase medium-chain family member 2 Neighboring gene predicted gene, 39078 Neighboring gene predicted gene, 39079 Neighboring gene predicted gene, 19950 Neighboring gene acyl-CoA synthetase medium-chain family member 4 Neighboring gene THUMP domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
GTP binding IEA
Inferred from Electronic Annotation
more info
 
acyl-CoA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acyl-CoA ligase activity ISO
Inferred from Sequence Orthology
more info
 
acyl-CoA ligase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
butyrate-CoA ligase activity ISO
Inferred from Sequence Orthology
more info
 
butyrate-CoA ligase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
fatty acid ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
fatty acid ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
fatty-acyl-CoA synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acyl-CoA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
fatty acid biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial matrix ISO
Inferred from Sequence Orthology
more info
 
mitochondrial matrix ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
mitochondrion HDA PubMed 

General protein information

Preferred Names
acyl-coenzyme A synthetase ACSM1, mitochondrial
Names
acetyl-Coenzyme A synthetase 3
butyrate--CoA ligase 1
butyryl Coenzyme A synthetase 1
butyryl-coenzyme A synthetase 1
lipoate-activating enzyme
middle-chain acyl-CoA synthetase 1
NP_473435.1
XP_006507277.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_054094.6NP_473435.1  acyl-coenzyme A synthetase ACSM1, mitochondrial

    See identical proteins and their annotated locations for NP_473435.1

    Status: VALIDATED

    Source sequence(s)
    AC134587
    Consensus CDS
    CCDS21783.1
    UniProtKB/Swiss-Prot
    Q91VA0
    Related
    ENSMUSP00000036140.6, ENSMUST00000047929.12
    Conserved Domains (2) summary
    COG0365
    Location:42566
    Acs; Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase [Lipid transport and metabolism]
    cl17068
    Location:42569
    AFD_class_I; Adenylate forming domain, Class I superfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

    Range
    119617763..119662515
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006507214.3XP_006507277.1  acyl-coenzyme A synthetase ACSM1, mitochondrial isoform X1

    Conserved Domains (2) summary
    COG0365
    Location:42438
    Acs; Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase [Lipid transport and metabolism]
    cl17068
    Location:42429
    AFD_class_I; Adenylate forming domain, Class I superfamily
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