Format

Send to:

Choose Destination

TADA1 transcriptional adaptor 1 [ Homo sapiens (human) ]

Gene ID: 117143, updated on 21-Dec-2019

Summary

Official Symbol
TADA1provided by HGNC
Official Full Name
transcriptional adaptor 1provided by HGNC
Primary source
HGNC:HGNC:30631
See related
Ensembl:ENSG00000152382 MIM:612763
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ADA1; HFI1; hADA1; STAF42; TADA1L
Summary
TADA1L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009]
Expression
Ubiquitous expression in brain (RPKM 9.2), bone marrow (RPKM 7.8) and 25 other tissues See more
Orthologs

Genomic context

See TADA1 in Genome Data Viewer
Location:
1q24.1
Exon count:
8
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (166856510..166876264, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (166825747..166845654, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene calponin 2 pseudogene 10 Neighboring gene pogo transposable element derived with KRAB domain Neighboring gene deoxyuridine triphosphatase pseudogene 6 Neighboring gene immunoglobulin like domain containing receptor 2 Neighboring gene maelstrom spermatogenic transposon silencer Neighboring gene Sharpr-MPRA regulatory region 1052 Neighboring gene RNA, 5S ribosomal pseudogene 65

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
contributes_to histone acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to histone acetyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription coactivator activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
histone H3 acetylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone H3 acetylation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of nucleic acid-templated transcription IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
SAGA complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
STAGA complex IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
 
focal adhesion IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
transcriptional adapter 1
Names
SPT3-associated factor 42 (STAF42)
transcriptional adapter 1-like protein
transcriptional adaptor 1 (HFI1 homolog, yeast)

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053053.4NP_444281.1  transcriptional adapter 1

    See identical proteins and their annotated locations for NP_444281.1

    Status: VALIDATED

    Source sequence(s)
    BC015401, CN399642
    Consensus CDS
    CCDS1255.1
    UniProtKB/Swiss-Prot
    Q96BN2
    Related
    ENSP00000356848.4, ENST00000367874.5
    Conserved Domains (1) summary
    pfam12767
    Location:7193
    SAGA-Tad1; Transcriptional regulator of RNA polII, SAGA, subunit

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    166856510..166876264 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center