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Slc7a9 solute carrier family 7 member 9 [ Rattus norvegicus (Norway rat) ]

Gene ID: 116726, updated on 17-Nov-2020

Summary

Official Symbol
Slc7a9provided by RGD
Official Full Name
solute carrier family 7 member 9provided by RGD
Primary source
RGD:619905
See related
Ensembl:ENSRNOG00000012344
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
amino acid transporter protein; exhibits high-affinity sodium-independent transport of cystine; may mediate reabsorption of cystine in the kidney proximal tubule [RGD, Feb 2006]
Expression
Restricted expression toward (RPKM 399.3) See more
Orthologs

Genomic context

See Slc7a9 in Genome Data Viewer
Location:
1q21
Exon count:
17
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (91709034..91738492)
106 current Rn_Celera (GCF_000002265.2) 1 AC_000069.1 (82459876..82482526)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (92836837..92865759)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene rhophilin, Rho GTPase binding protein 2 Neighboring gene FA core complex associated protein 24 Neighboring gene centrosomal protein 89 Neighboring gene 40S ribosomal protein S2 pseudogene Neighboring gene tudor domain containing 12 Neighboring gene nudix hydrolase 19

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Homology

Clone Names

  • MGC114282

Gene Ontology Provided by RGD

Function Evidence Code Pubs
L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
L-cystine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
L-cystine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
L-cystine transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
amino acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
neutral amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neutral amino acid transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
neutral amino acid transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 
peptide antigen binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
L-alpha-amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
L-cystine transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
L-cystine transport ISO
Inferred from Sequence Orthology
more info
 
L-cystine transport ISS
Inferred from Sequence or Structural Similarity
more info
 
amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
amino acid transport IDA
Inferred from Direct Assay
more info
PubMed 
neutral amino acid transport ISO
Inferred from Sequence Orthology
more info
 
neutral amino acid transport ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
apical plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
brush border membrane ISO
Inferred from Sequence Orthology
more info
 
brush border membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular_component ND
No biological Data available
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
B(0,+)-type amino acid transporter 1
Names
b(0,+)AT
glycoprotein-associated amino acid transporter b0,+AT1
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053929.1NP_446381.1  B(0,+)-type amino acid transporter 1

    See identical proteins and their annotated locations for NP_446381.1

    Status: PROVISIONAL

    Source sequence(s)
    AB029559
    UniProtKB/Swiss-Prot
    P82252
    Related
    ENSRNOP00000016919.2, ENSRNOT00000016919.4
    Conserved Domains (1) summary
    TIGR00911
    Location:13484
    2A0308; L-type amino acid transporter

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    91709034..91738492
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006228876.3XP_006228938.1  B(0,+)-type amino acid transporter 1 isoform X1

    See identical proteins and their annotated locations for XP_006228938.1

    UniProtKB/Swiss-Prot
    P82252
    Conserved Domains (1) summary
    TIGR00911
    Location:13484
    2A0308; L-type amino acid transporter
  2. XM_006228875.2XP_006228937.1  B(0,+)-type amino acid transporter 1 isoform X1

    See identical proteins and their annotated locations for XP_006228937.1

    UniProtKB/Swiss-Prot
    P82252
    Conserved Domains (1) summary
    TIGR00911
    Location:13484
    2A0308; L-type amino acid transporter
  3. XM_008759103.2XP_008757325.1  B(0,+)-type amino acid transporter 1 isoform X1

    See identical proteins and their annotated locations for XP_008757325.1

    UniProtKB/Swiss-Prot
    P82252
    Conserved Domains (1) summary
    TIGR00911
    Location:13484
    2A0308; L-type amino acid transporter
  4. XM_006228877.3XP_006228939.1  B(0,+)-type amino acid transporter 1 isoform X1

    See identical proteins and their annotated locations for XP_006228939.1

    UniProtKB/Swiss-Prot
    P82252
    Conserved Domains (1) summary
    TIGR00911
    Location:13484
    2A0308; L-type amino acid transporter
  5. XM_008759104.1XP_008757326.1  B(0,+)-type amino acid transporter 1 isoform X1

    See identical proteins and their annotated locations for XP_008757326.1

    UniProtKB/Swiss-Prot
    P82252
    Conserved Domains (1) summary
    TIGR00911
    Location:13484
    2A0308; L-type amino acid transporter
  6. XM_006228878.3XP_006228940.1  B(0,+)-type amino acid transporter 1 isoform X2

    Conserved Domains (1) summary
    TIGR00911
    Location:2396
    2A0308; L-type amino acid transporter

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    82459876..82482526
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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