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Foxj1 forkhead box J1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 116557, updated on 19-Apr-2019

Summary

Official Symbol
Foxj1provided by RGD
Official Full Name
forkhead box J1provided by RGD
Primary source
RGD:621764
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Hfh4; Hfh-4
Summary
putative transcription factor, may be involved in cell fate determination, lung development and/or spermatogenesis [RGD, Feb 2006]
Annotation information
Annotation category: partial on reference assembly
Expression
Biased expression in Lung (RPKM 72.9), Testes (RPKM 65.6) and 4 other tissues See more
Orthologs

Genomic context

See Foxj1 in Genome Data Viewer
Location:
10q32.1
Exon count:
2
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (105282090..105289396, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (104946564..104980556, complement)

Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene galanin receptor type 2 Neighboring gene exocyst complex component 7 Neighboring gene uncharacterized LOC108352160 Neighboring gene ring finger protein 157 Neighboring gene uncharacterized LOC102554855

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
actin cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
PubMed 
activation of GTPase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
brain development ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular response to insulin-like growth factor stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
central tolerance induction ISO
Inferred from Sequence Orthology
more info
PubMed 
cilium assembly ISO
Inferred from Sequence Orthology
more info
PubMed 
cilium assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
determination of left/right symmetry ISO
Inferred from Sequence Orthology
more info
PubMed 
epithelium development ISO
Inferred from Sequence Orthology
more info
PubMed 
establishment of apical/basal cell polarity ISO
Inferred from Sequence Orthology
more info
PubMed 
glomerular parietal epithelial cell development ISO
Inferred from Sequence Orthology
more info
PubMed 
heart development ISO
Inferred from Sequence Orthology
more info
PubMed 
humoral immune response ISO
Inferred from Sequence Orthology
more info
PubMed 
left/right pattern formation ISO
Inferred from Sequence Orthology
more info
PubMed 
leukocyte migration ISO
Inferred from Sequence Orthology
more info
PubMed 
lung epithelium development ISO
Inferred from Sequence Orthology
more info
PubMed 
metanephric part of ureteric bud development ISO
Inferred from Sequence Orthology
more info
PubMed 
motile cilium assembly ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of B cell activation ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of NF-kappaB transcription factor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of T cell differentiation in thymus ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of T cell proliferation ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of germinal center formation ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of humoral immune response mediated by circulating immunoglobulin ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of interleukin-6 biosynthetic process ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of central B cell tolerance induction ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of lung ciliated cell differentiation ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of epithelial cell differentiation ISO
Inferred from Sequence Orthology
more info
PubMed 
response to estradiol IEP
Inferred from Expression Pattern
more info
PubMed 
response to organic cyclic compound IEP
Inferred from Expression Pattern
more info
PubMed 
spermatogenesis IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
forkhead box protein J1
Names
hepatocyte nuclear factor 3 forkhead homolog 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053832.1NP_446284.1  forkhead box protein J1

    See identical proteins and their annotated locations for NP_446284.1

    Status: PROVISIONAL

    Source sequence(s)
    L36388
    UniProtKB/Swiss-Prot
    Q63247
    Conserved Domains (1) summary
    pfam00250
    Location:121207
    Forkhead; Forkhead domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

    Range
    105282090..105289396 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000078.1 Alternate Rn_Celera

    Range
    100138561..100142396 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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