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MRGPRE MAS related GPR family member E [ Homo sapiens (human) ]

Gene ID: 116534, updated on 23-Nov-2021

Summary

Official Symbol
MRGPREprovided by HGNC
Official Full Name
MAS related GPR family member Eprovided by HGNC
Primary source
HGNC:HGNC:30694
See related
Ensembl:ENSG00000184350 MIM:607232
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MGRF; MRGE; GPR167
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See MRGPRE in Genome Data Viewer
Location:
11p15.4
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (3225030..3232417, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (3246260..3253647, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene oxysterol binding protein like 5 Neighboring gene uncharacterized LOC107987158 Neighboring gene MRGPRG antisense RNA 1 Neighboring gene MAS related GPR family member G Neighboring gene NADH:ubiquinone oxidoreductase subunit A5 pseudogene 8 Neighboring gene NADH:ubiquinone oxidoreductase subunit A5 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
A genome-wide association study of brain lesion distribution in multiple sclerosis.
GeneReviews: Not available

General gene information

Markers

Homology

Clone Names

  • MGC138408

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mas-related G-protein coupled receptor member E
Names
G-protein coupled receptor 167
MAS-related GPR, member E
Mas-related G protein-coupled receptor F
mas-related G protein-coupled MRGE

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039165.4NP_001034254.2  mas-related G-protein coupled receptor member E

    See identical proteins and their annotated locations for NP_001034254.2

    Status: VALIDATED

    Source sequence(s)
    AC109309
    Consensus CDS
    CCDS41603.2
    UniProtKB/Swiss-Prot
    Q86SM8
    UniProtKB/TrEMBL
    W4VSQ4
    Related
    ENSP00000374482.6, ENST00000389832.7
    Conserved Domains (2) summary
    cd14964
    Location:5981
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:44294
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    3225030..3232417 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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