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F2rl3 F2R like thrombin or trypsin receptor 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 116498, updated on 10-Oct-2019

Summary

Official Symbol
F2rl3provided by RGD
Official Full Name
F2R like thrombin or trypsin receptor 3provided by RGD
Primary source
RGD:620872
See related
Ensembl:ENSRNOG00000048186
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
PAR4
Summary
G-protein-coupled receptor activated by thrombin and trypsin; mediates gastrointestinal motility [RGD, Feb 2006]
Expression
Biased expression in Spleen (RPKM 9.7), Thymus (RPKM 7.4) and 8 other tissues See more
Orthologs

Genomic context

See F2rl3 in Genome Data Viewer
Location:
16p14
Exon count:
2
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (18817797..18819790, complement)
106 current Rn_Celera (GCF_000002265.2) 16 AC_000084.1 (17341816..17343823, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 16 NC_005115.3 (18687984..18689977, complement)

Chromosome 16 - NC_005115.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102548312 Neighboring gene unconventional myosin-IXb-like Neighboring gene uncharacterized LOC103693913 Neighboring gene SIN3 transcription regulator family member B

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled receptor activity TAS
Traceable Author Statement
more info
PubMed 
thrombin-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
proteinase-activated receptor 4
Names
F2R like thrombin/trypsin receptor 3
PAR-4
coagulation factor II (thrombin) receptor-like 3
coagulation factor II receptor-like 3
protease-activated receptor 4
thrombin receptor-like 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053808.1NP_446260.1  proteinase-activated receptor 4

    See identical proteins and their annotated locations for NP_446260.1

    Status: PROVISIONAL

    Source sequence(s)
    AF269246
    UniProtKB/Swiss-Prot
    Q920E0
    Related
    ENSRNOP00000065190.1, ENSRNOT00000072664.2
    Conserved Domains (1) summary
    pfam00001
    Location:97342
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005115.4 Reference Rnor_6.0 Primary Assembly

    Range
    18817797..18819790 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000084.1 Alternate Rn_Celera

    Range
    17341816..17343823 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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